[HTML][HTML] Antiparasitics in animal health: quo vadis?

PM Selzer, C Epe - Trends in parasitology, 2021 - cell.com
Antiparasitics acting on endo-or ectoparasites represent the second largest segment of the
global animal health market, accounting for 23% of market share. However, relatively few …

Commercially approved vaccines for canine leishmaniosis: a review of available data on their safety and efficacy

R Velez, M Gállego - Tropical Medicine & International Health, 2020 - Wiley Online Library
Canine leishmaniosis is an important vector‐borne zoonosis caused mainly by Leishmania
infantum. Diagnosis and treatment of affected individuals can be particularly complex …

[HTML][HTML] An overview of the treatment of cutaneous leishmaniasis

TF Garza-Tovar, MI Sacriste-Hernández… - Faculty …, 2020 - ncbi.nlm.nih.gov
Leishmaniasis is a neglected tropical disease caused by species of Leishmania, with a
broad spectrum of clinical manifestations, such as cutaneous, visceral, and mucocutaneous …

[HTML][HTML] Revival of leishmanization and leishmanin

T Pacheco-Fernandez, G Volpedo… - Frontiers in Cellular …, 2021 - frontiersin.org
Leishmaniasis includes a spectrum of diseases ranging from debilitating cutaneous to fatal
visceral infections. This disease is caused by the parasitic protozoa of the genus Leishmania …

[HTML][HTML] Immunoinformatics Approach to Design a Multi-Epitope Nanovaccine against Leishmania Parasite: Elicitation of Cellular Immune Responses

M Margaroni, M Agallou, E Tsanaktsidou, O Kammona… - Vaccines, 2023 - mdpi.com
Leishmaniasis is a vector-borne disease caused by an intracellular parasite of the genus
Leishmania with different clinical manifestations that affect millions of people worldwide …

[HTML][HTML] Safety and immunogenicity of ChAd63-KH vaccine in post-kala-azar dermal leishmaniasis patients in Sudan

BM Younis, M Osman, EAG Khalil, F Santoro, S Furini… - Molecular therapy, 2021 - cell.com
Post-kala-azar dermal leishmaniasis (PKDL) is a chronic, stigmatizing skin condition
occurring frequently after apparent clinical cure from visceral leishmaniasis. Given an urgent …

Nano-co-delivery of lipophosphoglycan with soluble and autoclaved leishmania antigens into PLGA nanoparticles: Evaluation of in vitro and in vivo …

OA Tosyali, A Allahverdiyev, M Bagirova… - Materials Science and …, 2021 - Elsevier
The aim of the present study was to encapsulate lipophosphoglycan molecule (LPG) which
is one of the most immunogenic antigens of Leishmania parasites into PLGA nanoparticles …

[HTML][HTML] An immunoinformatic approach driven by experimental proteomics: in silico design of a subunit candidate vaccine targeting secretory proteins of Leishmania …

MAA Khan, JQ Ami, K Faisal, R Chowdhury, P Ghosh… - Parasites & vectors, 2020 - Springer
Background Visceral leishmaniasis (VL) caused by dimorphic Leishmania species is a
parasitic disease with high socioeconomic burden in endemic areas worldwide. Sustaining …

Isolation and functions of extracellular vesicles derived from parasites: the promise of a new era in immunotherapy, vaccination, and diagnosis

M Khosravi, ES Mirsamadi, H Mirjalali… - International journal of …, 2020 - Taylor & Francis
Experimental and epidemiological evidence shows that parasites, particularly helminths,
play a central role in balancing the host immunity. It was demonstrated that parasites can …

[HTML][HTML] Potential biomarkers of immune protection in human leishmaniasis

MN Rostami, A Khamesipour - Medical Microbiology and Immunology, 2021 - Springer
Leishmaniasis is a vector-borne neglected tropical disease endemic in over 100 countries
around the world. Available control measures are not always successful, therapeutic options …