Migration of hematopoietic stem cells through the blood, across the endothelial vasculature
to different organs and to their bone marrow (BM) niches, requires active navigation, a …

Haematopoietic cell transplantation (HCT) is the most widely used form of cellular therapy. It
is the only known cure for some haematological malignancies and has recently been used …

Background Cord-blood transplants are associated with delayed or failed engraftment in
about 20% of adult patients. The aim of this phase I/II study was to establish the safety and …

Introduction: One significant obstacle to the success of allogeneic hematopoietic stem cell
transplantation (HSCT) is represented by graft failure, defined as either lack of initial …

Background: Intravenous (IV) iron preparations are widely used in the treatment of anemia in
patients undergoing hemodialysis (HD). All IV iron preparations carry a risk of causing …

Human umbilical cord blood (HUCB) is now considered a valuable source for stem cell‐
based therapies. HUCB cells are enriched for stem cells that have the potential to initiate …

Use of unrelated umbilical cord blood cells (UCB) as an alternative source of hematopoietic
cell transplantation (HCT) has been widely used mainly for patients lacking an HLA-matched …

The use of umbilical cord blood (UCB) as an alternative haematopoietic cell source in lieu of
bone marrow for haematopoietic reconstitution is increasingly becoming a mainstay …

Background Unrelated cord blood transplantation (UCBT) is associated with delayed
hematopoietic recovery. Intrabone injection of cord blood cells (IB-UCBT) and double-UCBT …

The application of umbilical cord blood (UCB) as an important source of hematopoietic stem
and progenitor cells (HSPCs) for hematopoietic reconstitution in the clinical context has …