This year marks the 20th anniversary of functional near-infrared spectroscopy and imaging
(fNIRS/fNIRI). As the vast majority of commercial instruments developed until now are based …

Cerebrospinal fluid (CSF) is not stagnant but displays fascinating oscillatory flow patterns
inside the ventricular system and reversing fluid exchange between the cranial vault and …

The kinetics of amyloid beta turnover within human brain is still poorly understood. We
previously found a dramatic decline in the turnover of Aβ peptides in normal aging. It was not …

Schizophrenia seems to be a heterogeneous disorder. Emerging evidence indicates that
low level neuroinflammation (LLNI) may not occur infrequently. Many infectious agents with …

Three-D head geometrical models of eight healthy subjects and 11 hydrocephalus patients
were built using their CINE phase-contrast MRI data and used for computer simulations …

Spinal microstructures are known to substantially affect cerebrospinal fluid patterns, yet their
actual impact on flow resistance has not been quantified. Because the length scale of …

The brain lacks a conventional lymphatic system to remove metabolic waste. It has been
proposed that directional fluid movement through the arteriolar paravascular space (PVS) …

While there is growing experimental evidence that cerebrospinal fluid (CSF) flow induced by
the beating of ependymal cilia is an important factor for neuronal guidance, the respective …

Cerebrospinal fluid (CSF) dynamics in the cervical spinal subarachnoid space (SSS) have
been thought to be important to help diagnose and assess craniospinal disorders such as …

The aim of this work is to present an overview of recent advances in multi-scale modeling of
brain blood flow. In particular, we present some approaches that enable the in silico study of …