Objectives Hospital-associated disability (HAD), defined as loss of independence in
activities of daily living (ADL) following acute hospitalization, is observed among older …

Delirium is the most common neuropsychiatric syndrome found in the acute care setting,
with a prevalence ranging from 10% in general medicine to 85% in advanced cancer and …

The prevalence of delirium increases sharply with age, and about 20 percent of older
patients have delirium at the time of hospital admission for any reason. This review …

Delirium is a common and serious acute neuropsychiatric syndrome with core features of
inattention and global cognitive dysfunction. The etiologies of delirium are diverse and …

Background While delirium has been increasingly recognized as a serious and potentially
preventable condition, its long-term implications are not well understood. This study …

DESIGN: Prospective, randomized, blinded. SETTING: Inpatient academic tertiary medical
center. PARTICIPANTS: 126 consenting patients 65 and older (mean age 79±8 years, 79 …

Background. We examined the risk for postoperative delirium (POD) in patients with mild
cognitive impairment (MCI) or dementia, and the association between POD and subsequent …

Although a number of studies have documented the negative clinical and economic
consequences of delirium, interventions to prevent and treat delirium are infrequently …

Objective: Survivors of critical illness are frequently left with long-lasting disability. The
association between delirium and disability in critically ill patients has not been described …

The contribution of inflammation to the progression of neurodegenerative diseases such as
Alzheimer's, Parkinson's, and prion diseases is poorly understood. Brain inflammation in …