Mosquito-borne diseases, such as dengue and malaria, pose significant global health
burdens. Unfortunately, current control methods based on insecticides and environmental …

Arthropod crop pests are responsible for 20% of global annual crop losses, a figure
predicted to increase in a changing climate where the ranges of numerous species are …

We present tRNA-based vectors for producing multiple clustered regularly interspaced short
palindromic repeats (CRISPR) single guide RNAs (sgRNAs) from a single RNA polymerase …

CRISPR/Cas9 gene drive (CGD) promises to be a highly adaptable approach for spreading
genetically engineered alleles throughout a species, even if those alleles impair …

Interest in developing gene drive systems to control invasive species is growing, with New
Zealand reportedly considering the nascent technology as a way to locally eliminate the …

Gene drive organisms (GDOs), whose genomes have been genetically engineered to
spread a desired allele through a population, have the potential to transform the way …

The Atlantic salmon aquaculture industry still struggles with ectoparasitic sea lice despite
decades of research and development invested into louse removal methods. In contrast …

Recent reports have suggested that self-propagating CRISPR-based gene drive systems
are unlikely to efficiently invade wild populations due to drive-resistant alleles that prevent …

Invasive species are increasingly affecting agriculture, food, fisheries, and forestry resources
throughout the world. As a result of global trade, invasive species are often introduced into …

Herbicide resistant (HR) weeds are of major concern in modern agriculture. This situation is
exacerbated by the massive adoption of herbicide-based technologies along with the …