Brain and retinal pericytes: origin, function and role

A Trost, S Lange, F Schroedl, D Bruckner… - Frontiers in cellular …, 2016 - frontiersin.org
Pericytes are specialized mural cells located at the abluminal surface of capillary blood
vessels, embedded within the basement membrane. In the vascular network these …

The primary vascular dysregulation syndrome: implications for eye diseases

J Flammer, K Konieczka, AJ Flammer - EPMA Journal, 2013 - Springer
Vascular dysregulation refers to the regulation of blood flow that is not adapted to the needs
of the respective tissue. We distinguish primary vascular dysregulation (PVD, formerly called …

Dense dilated network with probability regularized walk for vessel detection

L Mou, L Chen, J Cheng, Z Gu… - IEEE transactions on …, 2019 - ieeexplore.ieee.org
The detection of retinal vessel is of great importance in the diagnosis and treatment of many
ocular diseases. Many methods have been proposed for vessel detection. However, most of …

Critical pathogenic events underlying progression of neurodegeneration in glaucoma

DJ Calkins - Progress in retinal and eye research, 2012 - Elsevier
Glaucoma is a common optic neuropathy with a complex etiology often linked to sensitivity to
intraocular pressure. Though the precise mechanisms that mediate or transduce this …

Characteristic patterns of dendritic remodeling in early-stage glaucoma: evidence from genetically identified retinal ganglion cell types

RN El-Danaf, AD Huberman - Journal of Neuroscience, 2015 - Soc Neuroscience
Retinal ganglion cell (RGC) loss is a hallmark of glaucoma and the second leading cause of
blindness worldwide. The type and timing of cellular changes leading to RGC loss in …

[HTML][HTML] Neurovascular dysfunction in glaucoma

L Alarcon-Martinez, Y Shiga… - Progress in Retinal and …, 2023 - Elsevier
Retinal ganglion cells, the neurons that die in glaucoma, are endowed with a high
metabolism requiring optimal provision of oxygen and nutrients to sustain their activity. The …

The neurovascular unit in glaucomatous neurodegeneration

LK Wareham, DJ Calkins - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
Glaucoma is a neurodegenerative disease of the visual system and leading cause of
blindness worldwide. The disease is associated with sensitivity to intraocular pressure (IOP) …

[HTML][HTML] Peripapillary retinal nerve fiber layer vascular microcirculation in glaucoma using optical coherence tomography–based microangiography

CL Chen, A Zhang, KD Bojikian, JC Wen… - … & visual science, 2016 - tvst.arvojournals.org
Purpose: To investigate the vascular microcirculation changes in the retinal nerve fiber layer
(RNFL) in normal, glaucoma suspect, and open-angle glaucoma (OAG) groups using optical …

Peripapillary retinal nerve fiber layer vascular microcirculation in eyes with glaucoma and single-hemifield visual field loss

CL Chen, KD Bojikian, JC Wen, Q Zhang… - JAMA …, 2017 - jamanetwork.com
Importance Understanding the differences in vascular microcirculation of the peripapillary
retinal nerve fiber layer (RNFL) between the hemispheres in eyes with glaucoma with single …

Reproducibility of retinal circulation measurements obtained using laser speckle flowgraphy-NAVI in patients with glaucoma

N Aizawa, Y Yokoyama, N Chiba… - Clinical …, 2011 - Taylor & Francis
Background: Laser speckle flowgraphy (LSFG) enables noninvasive quantification of the
retinal circulation in glaucoma patients. In this study, we tested the intrasession …