Cancer metastasis under the magnifying glass of epigenetics and epitranscriptomics
Most of the cancer-associated mortality and morbidity can be attributed to metastasis. The
role of epigenetic and epitranscriptomic alterations in cancer origin and progression has …
role of epigenetic and epitranscriptomic alterations in cancer origin and progression has …
CTSV (cathepsin V) promotes bladder cancer progression by increasing NF-κB activity
Y Xia, M Ge, L Xia, G Shan, H Qian - Bioengineered, 2022 - Taylor & Francis
Chronic inflammation is positively associated with the development of urinary bladder
cancer. However, its detailed regulatory mechanism remains elusive. The quantitative real …
cancer. However, its detailed regulatory mechanism remains elusive. The quantitative real …
APOBEC-1 Complementation Factor: From RNA Binding to Cancer
L Wang, Q Cheng - Cancer Control, 2024 - journals.sagepub.com
Background APOBEC-1 complementation factor (A1CF) and Apolipoprotein B mRNA editing
enzyme, catalytic polypeptide-1 (APOBEC-1) constitute the minimal proteins necessary for …
enzyme, catalytic polypeptide-1 (APOBEC-1) constitute the minimal proteins necessary for …
Bta-miR-34b inhibits proliferation and promotes apoptosis via the MEK/ERK pathway by targeting MAP2K1 in bovine primary Sertoli cells
L Zhang, T Ma, Q Tao, W Tan, H Chen… - Journal of Animal …, 2020 - academic.oup.com
Immature Sertoli cell (SC) proliferation determines the final number of mature SCs and
further regulates spermatogenesis. Accumulating evidence demonstrated that microRNAs …
further regulates spermatogenesis. Accumulating evidence demonstrated that microRNAs …
Smart-seq2 Technology Reveals a Novel Mechanism That Zearalenone Inhibits the In Vitro Maturation of Ovine Oocytes by Influencing TNFAIP6 Expression
Z Li, Y Liu, T Ma, C Lv, Y Li, H Duan, X Zhao, J Wang… - Toxins, 2023 - mdpi.com
Zearalenone (ZEN), a non-steroidal estrogenic fungal toxin widely present in forage, food,
and their ingredients, poses a serious threat to animal and human reproductive health. ZEN …
and their ingredients, poses a serious threat to animal and human reproductive health. ZEN …
Characterization of molecular subtypes based on chromatin regulators and identification of the role of NPAS2 in lung adenocarcinoma
Y Huang, L Xiao, MY Daba, D Xu, Y Wang, L Li, Q Li… - Clinical …, 2023 - Springer
Abstract Background Chromatin regulators (CRs) are critical epigenetic modifiers and have
been reported to play critical roles during the progression of various tumors, but their role in …
been reported to play critical roles during the progression of various tumors, but their role in …
Genetic alteration of mRNA editing enzyme APOBEC3B in the pathogenesis of ovarian endometriosis
V Balasubramanian, R Saravanan… - Reproductive …, 2024 - Elsevier
Research question What are the specific genetic alterations and associated network in
endometriotic cells responsible for the disease pathogenesis? Design Case control …
endometriotic cells responsible for the disease pathogenesis? Design Case control …
High APOBEC1 complementation factor expression positively modulates the proliferation, invasion, and migration of endometrial cancer cells through regulating P53 …
Q Liu, CY Chen, GL Chen - Cancer biotherapy & …, 2022 - liebertpub.com
Background: APOBEC1 complementation factor (A1CF) is a component of the
apolipoprotein-B messenger RNA editing complex that participates in various cellular …
apolipoprotein-B messenger RNA editing complex that participates in various cellular …
APOBEC1 complementation factor facilitates cell migration by promoting nucleus translocation of SMAD3 in renal cell carcinoma cells
H Xia, Y Liu, L Xu, H Mao, Q Zhou, Y Xie - In Vitro Cellular & …, 2021 - Springer
Metastasis is inevitable in about 30% of patients with primary renal cell carcinoma after
nephrectomy treatment. APOBEC1 complementation factor (A1CF), an RNA binding protein …
nephrectomy treatment. APOBEC1 complementation factor (A1CF), an RNA binding protein …
Combination of mTOR inhibitor PP242 and AMPK activator metformin exerts enhanced inhibitory effects on colorectal carcinoma cells in vitro by blocking multiple …
C Sun, X Yang, Z Jin, Z Gao - Journal of Chemotherapy, 2023 - Taylor & Francis
The second-generation mammalian target of rapamycin (mTOR) inhibitor PP242 has
demonstrated limited success in some rapamycin-insensitive tumours. We examined the …
demonstrated limited success in some rapamycin-insensitive tumours. We examined the …