This review focuses on metabolomics from an NMR point of view. It attempts to cover the
broad scope of metabolomics and describes the NMR experiments that are most suitable for …

Noncanonical amino acids (ncAAs) are synthetic building blocks that, when incorporated
into proteins, confer novel functions and enable precise control over biological processes …

Visualization and quantification of important biomolecules like glutathione (GSH) in live cells
are highly important. The existing methods are mostly from optical detection and lack of …

In‐cell NMR spectroscopy is an effective tool for observing proteins at atomic resolution in
their native cellular environment. However, its utility is limited by its low sensitivity and the …

In-cell NMR, ie, NMR spectroscopy applied to studying specific macromolecules within living
cells, is becoming the technique of choice for the structural and mechanistic description of …

The possibility of using selectively incorporated 19F nuclei for NMR spectroscopic studies
has retrieved increasing interest in recent years. The high gyromagnetic ratio of 19F and its …

Paucity of efficient probes and small molecule ligands that can distinguish different G-
quadruplex (GQ) topologies poses challenges not only in understanding their basic structure …

Herein we describe a method for the efficient production (∼ 90% fluorination) of 5-F-Trp
human H ferritin via the selective incorporation of 19 F into the side chain of W93 using 5 …

19F NMR spectroscopy has recently witnessed a resurgence as an attractive analytical tool
for the study of the structure and dynamics of biomolecules in vitro and in cells, despite …

Fluorinated aromatic amino acids (FAAs) are promising tools when studying protein
structure and dynamics by NMR spectroscopy. The incorporation FAAs in mammalian …