Astrocyte swelling occurs after central nervous system injury and contributes to brain
swelling, which can increase mortality. Mechanisms proffered to explain astrocyte swelling …

The first human mutations in GATA6 were described in a cohort of patients with persistent
truncus arteriosus, and the phenotypic spectrum has expanded since then. This study …

A major limitation in studies of the injured heart is animal-to-animal variability in wound size
resulting from commonly used techniques such as left anterior descending coronary artery …

Congenital bicuspid aortic valve (BAV), the most common form of birth defect in humans, is
associated with substantial morbidity and mortality. Increasing evidence demonstrates that …

Congenital heart disease (CHD) is the most common form of developmental malformation
and is the leading noninfectious cause of infant mortality. Emerging evidence indicates that …

Background The GATA-binding factor 6 (Gata6) gene encodes a zinc finger transcription
factor that often functions as a key regulator of lineage specification during development. It is …

Ventricular septal defect (VSD) is the most common form of congenital cardiovascular
malformation and an important contributor to the substantially increased morbidity and …

Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease associated
with significant morbidity and mortality in humans. However, the molecular etiology …

Atrial fibrillation (AF) is the most common type of cardiac arrhythmia, occurring in 1% to 2%
of the general population. The prevalence of AF increases with age, ranging from b1% in …

Atrial fibrillation (AF) is the most common type of sustained cardiac arrhythmia and is
associated with substantial morbidity and mortality. Increasing evidence demonstrates that …