Membrane proteins play a most important part in metabolism, signaling, cell motility,
transport, development, and many other biochemical and biophysical processes which …

A new and promising tool in membrane research is the detergent-free solubilization of
membrane proteins by styrene–maleic acid copolymers (SMAs). These amphipathic …

Membrane proteins play critical physiological roles in all organisms, from ion transport and
signal transduction to multidrug resistance. Elucidating their 3D structures is essential for …

Monitoring food freshness/spoilage is important to ensure food quality and safety. Current
methods of food quality monitoring are mostly time-consuming and labor intensive …

The styrene-maleic acid (SMA) copolymer is rapidly gaining attention as a tool in membrane
research, due to its ability to directly solubilize lipid membranes into nanodisk particles …

Amphipathic styrene-maleic acid (SMA) copolymers directly solubilize biomembranes into
SMA-lipid particles, or SMALPs, that are often regarded as nanodiscs and hailed as a native …

Integral membrane proteins pose considerable challenges to mass spectrometry (MS) owing
to the complexity and diversity of the components in their native environment. Here, we use …

G protein-coupled receptors (GPCRs) are a large family of integral membrane proteins
which conduct a wide range of biological roles and represent significant drug targets. Most …

G protein-coupled receptors (GPCRs) are the largest and a diverse family of proteins
involved in signal transduction across biological membranes. GPCRs mediate a wide range …

Alpha transmembrane proteins (αTMPs) profoundly affect many critical biological processes
and are major drug targets due to their pivotal protein functions. At present, even though the …