The immune-inflammatory response is associated with increased nitro-oxidative stress. The
aim of this mechanistic review is to examine:(a) the role of redox-sensitive transcription …

Neutrophils are the most abundant circulating leukocytes, being the first line of defence
against bacterial and fungal infections. However, neutrophils also contribute to tissue …

Sepsis is a persistent systemic inflammatory condition involving multiple organ failures
resulting from a dysregulated immune response to infection, and one of the hallmarks of …

Neutrophils are an absolutely essential part of the innate immune system, playing an
essential role in the control of infectious diseases but more recently are also being viewed …

Hydrogen sulfide (H 2 S) is now recognized as an endogenous signaling gasotransmitter in
mammals. It is produced by mammalian cells and tissues by various enzymes …

This study shows that the supramolecular arrangement of proteins in nanoparticle structures
predicts nanoparticle accumulation in neutrophils in acute lung inflammation (ALI). We …

Infections, cardiovascular disease, and cancer are major causes of disease and death
worldwide. Neutrophils are inescapably associated with each of these health concerns, by …

Sepsis is characterized by a dysregulated immune response to infections that causes life-
threatening organ dysfunction and even death. When infections occur, bacterial cell wall …

Sepsis remains a leading cause of death worldwide, despite advances in critical care, and
understanding of the pathophysiology and treatment strategies. No specific therapy or drugs …

Pyroptosis is a caspase-1 or caspase-4/5/11-dependent programmed cell death associated
with inflammation, which is initiated by inflammasomes or cytosolic LPS in innate immunity …