Cell growth and gene expression, two essential elements of all living systems, have long
been the focus of biophysical interrogation. Advances in experimental single-cell methods …

Defining the cellular factors that drive growth rate and proteome composition is essential for
understanding and manipulating cellular systems. In bacteria, ribosome concentration is …

Cell size regulation arises from physical manifestations of cell proliferation and metabolic
pathways. On one hand, coordination between these systems yields a constant cell size …

Cell size is tightly controlled in healthy tissues and single-celled organisms, but it remains
unclear how cell size influences physiology. Increasing cell size was recently shown to …

Mammalian cells rapidly respond to environmental changes by altering transmembrane
water and ion fluxes, changing cell volume. Contractile forces generated by actomyosin …

Cellular senescence is a recently emerged research topic in modern biology. Often
described as a double-edged sword, it encompasses numerous essential biological …

Science foremost derives from our curiosity about the world. Can we make sense of the
phenomena we see around us? Given that understanding, can we predict previously …

Exponential accumulation of cell size and highly expressed proteins is observed in many
bacterial species at the single cell level. Exponential rates exhibit cycle-by-cycle fluctuations …

Cell growth and division must be coordinated to maintain a stable cell size, but how this
coordination is implemented in multicellular tissues remains unclear. In unicellular …

Measurements of cell size dynamics have revealed phenomenological principles by which
individual cells control their size across diverse organisms. One of the emerging paradigms …