K Ueda, KJ Black - Journal of clinical medicine, 2021 - mdpi.com
Tics are characterized by sudden, rapid, recurrent, nonrhythmic movement or vocalization, and are the most common movement disorders in children. Their onset is usually in …
We previously established the contribution of de novo damaging sequence variants to Tourette disorder (TD) through whole-exome sequencing of 511 trios. Here, we sequence …
D Enoch, BK Puri, H Ball - 2020 - taylorfrancis.com
This book explores the historical background to, and present-day understanding of, a number of unusual psychiatric disorders. This fully revised new edition contains a new …
KA Johnson, PT Fletcher, D Servello, A Bona… - Journal of Neurology …, 2019 - jnnp.bmj.com
Background Deep brain stimulation (DBS) can be an effective therapy for tics and comorbidities in select cases of severe, treatment-refractory Tourette syndrome (TS). Clinical …
F Augustine, HS Singer - Tremor and Other Hyperkinetic …, 2019 - pmc.ncbi.nlm.nih.gov
Background Anatomically, cortical-basal ganglia-thalamo-cortical (CBGTC) circuits have an essential role in the expression of tics. At the biochemical level, the proper conveyance of …
J Jankovic, B Coffey, DO Claassen… - JAMA network …, 2021 - jamanetwork.com
Importance Tourette syndrome is a neurodevelopmental disorder characterized by childhood onset of motor and phonic tics; treatments for tics are associated with safety …
J Jankovic - Journal of Neural Transmission, 2020 - Springer
Motor and phonic tics associated with Tourette syndrome (TS) can range in severity from barely perceptible to disabling and most patients have a variety of behavioral co-morbidities …
Y Liu, J Xu, K Fang, Y Xu, J Gao… - Therapeutic …, 2021 - journals.sagepub.com
Background: Antipsychotic agents (APS) are widely used drugs to treat psychotic symptoms and can effectively reduce both positive and negative symptoms of schizophrenia. For …
J Frey, IA Malaty - Current Neurology and Neuroscience Reports, 2022 - Springer
Abstract Purpose of Review This study aims to examine the treatments currently available for Tourette syndrome (TS) and to discuss evolving therapies, spanning behavioral …