Cognitive changes associated with cancer and cancer treatments have become an
increasing concern. Using breast cancer as the prototype, we reviewed the research from …

This review article summarizes how frailty can be considered in relation to deficit
accumulation. Recalling that frailty is an age-associated, nonspecific vulnerability, we …

Background DNA methylation changes with age. Chronological age predictors built from
DNA methylation are termed 'epigenetic clocks'. The deviation of predicted age from the …

OBJECTIVES: To evaluate the prevalence and 10‐year outcomes of frailty in older adults in
relation to deficit accumulation. DESIGN: Prospective cohort study. SETTING: The National …

Frailty is a common clinical syndrome in older adults, which carries an increased risk for
poor health outcomes, including falls, incident disability, hospitalization, and mortality. 1–5 …

Antiaging therapies show promise in model organism research. Translation to humans is
needed to address the challenges of an aging global population. Interventions to slow …

Different theories posit that aging is caused by molecular damage, genetic programs,
continued development, hyperfunction, antagonistic pleiotropy alleles, mutations, trade‐offs …

Background People age at remarkably different rates, but how to estimate trajectories of
senescence is controversial. Methods In a secondary analysis of a representative cohort of …

В монографии проанализированы основные концепции о природе старения, история
их возникновения и эволюция. Изложены современные представления о …

Post‐reproductive longevity is a robust feature of human life and not only a recent
phenomenon caused by improvements in sanitation, public health, and medical advances …