Metabolic engineering for high yield synthesis of astaxanthin in Xanthophyllomyces dendrorhous

A Torres-Haro, J Verdín, MR Kirchmayr… - Microbial Cell …, 2021 - Springer
Astaxanthin is a carotenoid with a number of assets useful for the food, cosmetic and
pharmaceutical industries. Nowadays, it is mainly produced by chemical synthesis …

Biosynthesis of astaxanthin by using industrial yeast

D Zhou, X Yang, H Wang, Y Jiang… - Biofuels, Bioproducts …, 2023 - Wiley Online Library
Astaxanthin has been widely applied in feed additives and the medical industry due to its
antioxidant, coloring, and health‐promoting properties. Traditional processes for astaxanthin …

Metabolic Engineering of Chlamydomonas reinhardtii for Enhanced β-Carotene and Lutein Production

JP Rathod, C Vira, AM Lali, G Prakash - Applied biochemistry and …, 2020 - Springer
The metabolic engineering of Chlamydomonas reinhardtii, one of the fastest-growing
microalgae, is a potential alternative for enhanced carotenoid productivity. CrtYB (phytoene …

One-step integration of multiple genes into the oleaginous yeast Yarrowia lipolytica

S Gao, L Han, L Zhu, M Ge, S Yang, Y Jiang… - Biotechnology letters, 2014 - Springer
Yarrowia lipolytica is an unconventional yeast, and is generally recognized as safe (GRAS).
It provides a versatile fermentation platform that is used commercially to produce many …

Proteomic and metabolomic analysis of the carotenogenic yeast Xanthophyllomyces dendrorhous using different carbon sources

P Martinez-Moya, K Niehaus, J Alcaíno, M Baeza… - BMC genomics, 2015 - Springer
Background Astaxanthin is a potent antioxidant with increasing biotechnological interest. In
Xanthophyllomyces dendrorhous, a natural source of this pigment, carotenogenesis is a …

Combined 6-benzylaminopurine and H2O2 stimulate the astaxanthin biosynthesis in Xanthophyllomyces dendrorhous

A Torres-Haro, J Verdín, MR Kirchmayr… - Applied Microbiology …, 2024 - Springer
Astaxanthin is one of the most attractive carotenoids due to its high antioxidant activity and
beneficial biological properties, while Xanthophyllomyces dendrorhous is one of its main …

Strategy and regulatory mechanisms of glutamate feeding to enhance astaxanthin yield in Xanthophyllomyces dendrorhous

B Wang, X Pan, J Jia, W Xiong, E Manirafasha… - Enzyme and Microbial …, 2019 - Elsevier
Xanthophyllomyces dendrorhous is an excellent industrial source for production of natural
astaxanthin, but the yield of astaxanthin is relative low due to the contradiction between …

Metabolic engineering for the microbial production of marine bioactive compounds

X Mao, Z Liu, J Sun, SY Lee - Biotechnology Advances, 2017 - Elsevier
Many marine bioactive compounds have medicinal and nutritional values. These bioactive
compounds have been prepared using solvent-based extraction from marine bio-resources …

The Involvement of Mig1 from Xanthophyllomyces dendrorhous in Catabolic Repression: An Active Mechanism Contributing to the Regulation of Carotenoid …

J Alcaíno, N Bravo, P Córdova, AE Marcoleta… - PloS one, 2016 - journals.plos.org
The red yeast X. dendrorhous is one of the few natural sources of astaxanthin, a carotenoid
used in aquaculture for salmonid fish pigmentation and in the cosmetic and pharmaceutical …

Codon usage and codon context bias in Xanthophyllomyces dendrorhous

M Baeza, J Alcaíno, S Barahona, D Sepúlveda… - BMC genomics, 2015 - Springer
Background Synonymous codons are used differentially in organisms from the three
domains of life, a phenomenon referred to as codon usage bias. In addition, codon pair bias …