Recent Advances in Crimean-Congo Hemorrhagic Fever Virus Detection, Treatment, and Vaccination: Overview of Current Status and Challenges

K Muzammil, S Rayyani, A Abbas Sahib… - Biological Procedures …, 2024 - Springer
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne virus, and zoonosis, and
affects large regions of Asia, Southwestern and Southeastern Europe, and Africa. CCHFV …

Replicating RNA vaccination elicits an unexpected immune response that efficiently protects mice against lethal Crimean-Congo hemorrhagic fever virus challenge

SS Leventhal, K Meade-White, D Rao, E Haddock… - …, 2022 - thelancet.com
Summary Background Crimean-Congo hemorrhagic fever virus is the cause of a severe
hemorrhagic fever with cases reported throughout a wide-geographic region. Spread by the …

The seroprevalence of Crimean-Congo Hemorrhagic Fever in wild and domestic animals: an epidemiological update for domestic animals and first seroevidence in …

C Nurettin, B Engin, T Sukru, A Munir, V Zati… - Veterinary Sciences, 2022 - mdpi.com
Simple Summary Crimean-Congo hemorrhagic fever is a tick-borne and zoonotic emerging
viral disease that is characterized by the sudden development of high fever and vascular …

[HTML][HTML] The Role of Nucleocapsid Protein (NP) in the Immunology of Crimean–Congo Hemorrhagic Fever Virus (CCHFV)

A Pirincal, MZ Doymaz - Viruses, 2024 - mdpi.com
Crimean–Congo hemorrhagic fever virus (CCHFV) is an orthonairovirus from the
Bunyavirales order that is widely distributed geographically and causes severe or fatal …

Immunogenicity of a DNA-based Sindbis replicon expressing Crimean–Congo hemorrhagic fever virus nucleoprotein

T Tipih, M Heise, FJ Burt - Vaccines, 2021 - mdpi.com
Crimean–Congo hemorrhagic fever virus (CCHFV) infrequently causes hemorrhagic fever in
humans with a case fatality rate of 30%. Currently, there is neither an internationally …

Development of anti-Crimean-Congo hemorrhagic fever virus Gc and NP-specific ELISA for detection of antibodies in domestic animal sera

S Belij-Rammerstorfer, G Limon, EA Maze… - Frontiers in Veterinary …, 2022 - frontiersin.org
Crimean-Congo hemorrhagic fever (CCHF) is a priority emerging disease. CCHF, caused by
the CCHF virus (CCHFV), can lead to hemorrhagic fever in humans with severe cases often …

Deciphering antibody responses to orthonairoviruses in ruminants

J Hartlaub, M Keller, MH Groschup - Microorganisms, 2021 - mdpi.com
Antibody cross-reactivities between related viruses are common diagnostic challenges,
resulting in reduced diagnostic specificities and sensitivities. In this study, antibody cross …

Evaluation of the immunogenicity of vaccine candidates developed using a baculovirus surface display system for Crimean-Congo hemorrhagic fever virus in mice

G Zhang, P Wang, L Jiang, S Wang, S Zhang… - Frontiers in …, 2023 - frontiersin.org
Crimean-Congo hemorrhagic fever (CCHF), which has a fatality rate of 20–30%, is widely
prevalent in several regions in Asia, Europe, and Africa and has spread to a wider range of …

Comparative characterization of Crimean-Congo hemorrhagic fever virus cell culture systems with application to propagation and titration methods

H Li, G Smith, M Goolia, P Marszal, BS Pickering - Virology Journal, 2023 - Springer
Crimean-Congo hemorrhagic fever orthonairovirus (CCHFV) is a biosafety level 4 and World
Health Organization top priority pathogen. Infection leads to an often fatal hemorrhagic fever …

Mapping of Antibody Epitopes on the Crimean-Congo Hemorrhagic Fever Virus Nucleoprotein

BP Lombe, T Saito, H Miyamoto, A Mori-Kajihara… - Viruses, 2022 - mdpi.com
Crimean-Congo hemorrhagic fever virus (CCHFV), a nairovirus, is a tick-borne zoonotic
virus that causes hemorrhagic fever in humans. The CCHFV nucleoprotein (NP) is the …