[HTML][HTML] Breast cancer—epidemiology, risk factors, classification, prognostic markers, and current treatment strategies—an updated review

S Łukasiewicz, M Czeczelewski, A Forma, J Baj… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer is the most common cancer among women. It is estimated
that 2.3 million new cases of BC are diagnosed globally each year. Based on mRNA gene …

[HTML][HTML] Inflammation after spinal cord injury: a review of the critical timeline of signaling cues and cellular infiltration

DJ Hellenbrand, CM Quinn, ZJ Piper… - Journal of …, 2021 - Springer
Traumatic spinal cord injury (SCI) is a devastating neurological condition that results in a
loss of motor and sensory function. Although extensive research to develop treatments for …

ECM-mimetic immunomodulatory hydrogel for methicillin-resistant Staphylococcus aureus–infected chronic skin wound healing

W Liu, R Gao, C Yang, Z Feng, W Ou-Yang, X Pan… - Science …, 2022 - science.org
The treatment of difficult-to-heal wounds remains a substantial clinical challenge due to
deteriorative tissue microenvironment including the loss of extracellular matrix (ECM) …

[HTML][HTML] Biofilm microenvironment triggered self-enhancing photodynamic immunomodulatory microneedle for diabetic wound therapy

L Yang, D Zhang, W Li, H Lin, C Ding, Q Liu… - Nature …, 2023 - nature.com
The treatment of diabetic wounds faces enormous challenges due to complex wound
environments, such as infected biofilms, excessive inflammation, and impaired …

Exosome-mediated genetic reprogramming of tumor-associated macrophages by exoASO-STAT6 leads to potent monotherapy antitumor activity

S Kamerkar, C Leng, O Burenkova, SC Jang… - Science …, 2022 - science.org
Effectiveness of checkpoint immunotherapy in cancer can be undermined by
immunosuppressive tumor-associated macrophages (TAMs) with an M2 phenotype …

Engineering bioactive M2 macrophage‐polarized anti‐inflammatory, antioxidant, and antibacterial scaffolds for rapid angiogenesis and diabetic wound repair

Z Tu, M Chen, M Wang, Z Shao, X Jiang… - Advanced Functional …, 2021 - Wiley Online Library
Diabetic wound healing still faces great challenges due to the excessive inflammation, easy
infection, and impaired angiogenesis in wound beds. The immunoregulation of …

[HTML][HTML] Exosomes from TNF-α-treated human gingiva-derived MSCs enhance M2 macrophage polarization and inhibit periodontal bone loss

Y Nakao, T Fukuda, Q Zhang, T Sanui, T Shinjo, X Kou… - Acta biomaterialia, 2021 - Elsevier
Mesenchymal stem cell (MSC)–derived exosome plays a central role in the cell-free
therapeutics involving MSCs and the contents can be customized under disease-associated …

Pulmonary fibrosis in COVID‐19 survivors: Predictive factors and risk reduction strategies

AS Ojo, SA Balogun, OT Williams… - Pulmonary medicine, 2020 - Wiley Online Library
Although pulmonary fibrosis can occur in the absence of a clear‐cut inciting agent, and
without a clinically clear initial acute inflammatory phase, it is more commonly associated …

[HTML][HTML] Macrophage polarization and metabolism in atherosclerosis

P Hou, J Fang, Z Liu, Y Shi, M Agostini… - Cell Death & …, 2023 - nature.com
Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of fatty
deposits in the inner walls of vessels. These plaques restrict blood flow and lead to …

[HTML][HTML] Macrophages as a therapeutic target to promote diabetic wound healing

M Sharifiaghdam, E Shaabani, R Faridi-Majidi… - Molecular Therapy, 2022 - cell.com
It is well‏‏ established that macrophages are key regulators of wound healing, displaying
impressive plasticity and an evolving phenotype, from an aggressive pro-inflammatory or" …