Effects of experimental sleep deprivation on anxiety-like behavior in animal research: Systematic review and meta-analysis

GN Pires, AG Bezerra, S Tufik, ML Andersen - … & Biobehavioral Reviews, 2016 - Elsevier
Increased acute anxiety is a commonly reported behavioral consequence of sleep
deprivation in humans. However, rodent studies conducted so far produced inconsistent …

Pathological consequences of intermittent hypoxia in the central nervous system

SXL Zhang, Y Wang, D Gozal - Comprehensive Physiology, 2012 - Wiley Online Library
Intermittent hypoxia (IH) is a frequent occurrence in clinical settings. In the last decades,
evidence has emerged implicating the gas exchange alterations and sleep disruption …

High altitude exposure impairs sleep patterns, mood, and cognitive functions

V de Aquino Lemos, HKM Antunes… - …, 2012 - Wiley Online Library
This work evaluated the importance of sleep on mood and cognition after 24 h of exposure
to hypoxia. Ten males, aged 23–30 years, were placed in a normobaric chamber simulating …

Involvement of NOX2 in the development of behavioral and pathologic alterations in isolated rats

S Schiavone, S Sorce, M Dubois-Dauphin, V Jaquet… - Biological …, 2009 - Elsevier
BACKGROUND: Social stress leads to oxidative stress in the central nervous system,
contributing to the development of mental disorders. Loss of parvalbumin in interneurons is …

Paradoxical sleep deprivation impairs acquisition, consolidation, and retrieval of a discriminative avoidance task in rats

TA Alvarenga, CL Patti, ML Andersen, RH Silva… - Neurobiology of learning …, 2008 - Elsevier
The aim of the present study was to investigate the effects of paradoxical sleep deprivation
(PSD) for 96h on the learning/memory processes in rats submitted to the plus-maze …

NADPH oxidase elevations in pyramidal neurons drive psychosocial stress-induced neuropathology

S Schiavone, V Jaquet, S Sorce… - Translational …, 2012 - nature.com
Oxidative stress is thought to be involved in the development of behavioral and
histopathological alterations in animal models of psychosis. Here we investigate the causal …

[HTML][HTML] The prevalence of anxiety and depression symptoms in obstructive sleep apnea

W Akberzie, S Hesselbacher, I Aiyer, S Surani… - Cureus, 2020 - ncbi.nlm.nih.gov
Objectives Mood disorders are common in obstructive sleep apnea (OSA), though the
interactions are not well-understood. The objective of this study was to evaluate the …

[HTML][HTML] Distinct effects of acute and chronic sleep loss on DNA damage in rats

ML Andersen, DA Ribeiro, CT Bergamaschi… - Progress in Neuro …, 2009 - Elsevier
The aim of this investigation was to evaluate genetic damage induced in male rats by
experimental sleep loss for short-term (24 and 96 h) and long-term (21 days) intervals, as …

Short-term sleep fragmentation enhances anxiety-related behavior: The role of hormonal alterations

Z Grubac, N Sutulovic, A Ademovic, M Velimirovic… - PLoS …, 2019 - journals.plos.org
Introduction The neuroendocrine background of acute sleep fragmentation in obstructive
sleep apnea and sleep fragmentation involvement in psychiatric comorbidities, common in …

Anxiogenic Potential of Experimental Sleep Fragmentation Is Duration‐Dependent and Mediated via Oxidative Stress State

Ž Grubač, N Šutulović, S Šuvakov… - Oxidative Medicine …, 2021 - Wiley Online Library
Sleep architecture alterations, among which sleep fragmentation is highly prevalent,
represent risk factors for a variety of diseases, ranging from cardiovascular to brain …