The pace of change in chemical and biological research enabled by improved detection
systems demands fundamental liquid handling and sample preparation changes. The …

Finding potent multidrug combinations against cancer and infections is a pressing
therapeutic challenge; however, screening all combinations is difficult because the number …

Quiescent cancer cells in malignant tumors can withstand cell-cycle active treatment and
cause cancer spread and recurrence. Three-dimensional (3D) cancer cell models have led …

Ferroptosis induction is an emerging strategy to treat cancer and contrast the tricky issue of
chemoresistance, which can arise towards apoptosis. This work elucidates the anticancer …

Liquid handling instruments for life science applications based on droplet formation with
focused acoustic energy or acoustic droplet ejection (ADE) were introduced commercially …

Dogs with B-cell lymphoma typically respond well to first-line CHOP-based chemotherapy,
but there is no standard of care for relapsed patients. To help veterinary oncologists select …

Cocktails of drugs can be more effective than single drugs, because they can potentially
work at lower doses and avoid resistance. However, it is impossible to test all drug cocktails …

Current treatment strategies for chemotherapy of cancer patients were developed to benefit
groups of patients with similar clinical characteristics. In practice, response is very …

Background: Drugs for targeted therapies are primarily Small Molecules Inhibitors (SMIs),
monoclonal antibodies (mAbs), interfering RNA molecules and microRNA. The use of these …

Despite of remarkable progress made in the head and neck cancer (HNC) therapy, the
survival rate of this metastatic disease remain low. Tailoring the appropriate therapy to …