Expression, regulation, and function of progesterone receptors in bovine cumulus oocyte complexes during in vitro maturation

IM Aparicio, M Garcia-Herreros, LC O'shea… - Biology of …, 2011 - academic.oup.com
Progesterone (P4) exerts its effects by binding to specific genomic (nPR-A/B) and non-
genomic (mPRalpha/beta, PGRMC1/2) receptors. P4 has a role in the regulation of the …

Plasma progesterone concentrations in the mid-luteal phase are dependent on luteal size, but independent of luteal blood flow and gene expression in lactating dairy …

J Lüttgenau, SE Ulbrich, N Beindorff, A Honnens… - Animal Reproduction …, 2011 - Elsevier
The objective of the present study was to investigate if plasma progesterone (pP4)
concentrations are dependent on luteal size, blood flow, or gene expression in luteal tissue …

Lactylation drives hCG-triggered luteinization in hypoxic granulosa cells

G Wu, Y Pan, M Chen, Z Liu, C Li, Y Sheng, H Li… - International Journal of …, 2024 - Elsevier
Hypoxia that occurs during the luteinization process of granulosa cells (GC) contributes to
the formation of lactate in follicles. Lysine lactylation (Kla), a post-translational modification …

Gonadal sex steroids: production, action and interactions in mammals

ZT Ruiz-Cortés - Steroids-from physiology to clinical medicine, 2012 - books.google.com
There are five major classes of steroid hormones: testosterone (androgen), estradiol (estro‐-
gen), progesterone (progestin), cortisol/corticosterone (glucocorticoid), and aldosterone …

Effect of PGC-1α overexpression or silencing on mitochondrial apoptosis of goat luteinized granulosa cells

GM Zhang, MT Deng, YL Zhang, YX Fan… - Journal of bioenergetics …, 2016 - Springer
During goat follicular development, abnormal expression of peroxisome proliferator-
activated receptor gamma coactivator-1 alpha (PGC-1α) in granulosa cells (GCs) may …

Meta-analysis to determine effects of treatment with FSH when there is progestin-priming on in-vitro embryo production using ovum pick-up in Bos taurus cows

Z Sarwar, M Sagheer, F Sosa, M Saad… - Animal Reproduction …, 2020 - Elsevier
Treatments with follicle stimulating hormone (FSH) to enhance ovarian follicular
development before ovum pick-up (OPU) are important for improving in-vitro embryo …

Increasing cell plating density mimics an early post-LH stage in cultured bovine granulosa cells

A Baufeld, J Vanselow - Cell and tissue research, 2013 - Springer
Cultured ovarian granulosa cells are essential models to study molecular mechanisms of
gene regulation during folliculogenesis. Here, we characterize primary tissue culture models …

Effects of Notch2 on proliferation, apoptosis and steroidogenesis in bovine luteinized granulosa cells

Y Li, J Jing, W Dang, Q Han, X Guo, K Jia, Y Cheng… - Theriogenology, 2021 - Elsevier
Notch signaling pathway plays an important regulatory role in the development of
mammalian follicles. This study aimed to explore the effect of Notch2 on the function of …

Synergistic effect of standardized extract of Asparagus officinalis stem and heat shock on progesterone synthesis with lipid droplets and mitochondrial function in …

KT Ho, AZ Balboula, K Homma, J Takanari… - The Journal of Steroid …, 2023 - Elsevier
Progesterone (P4) is a well-known steroid hormone that plays a key role in oocyte growth
and the maintenance of pregnancy in mammals, including cattle. Heat stress (HS) has an …

Inflammation during oocyte maturation reduces developmental competence and increases apoptosis in blastocysts

A Tariq, ZK Seekford, JJ Bromfield - Biology of Reproduction, 2024 - academic.oup.com
Uterine infections cause ovarian dysfunction and infertility. The bacterial endotoxin,
lipopolysaccharide (LPS), accumulates in the follicular fluid of dominant follicles of cows with …