Stilbenes: Source plants, chemistry, biosynthesis, pharmacology, application and problems related to their clinical Application-A comprehensive review

T Teka, L Zhang, X Ge, Y Li, L Han, X Yan - Phytochemistry, 2022 - Elsevier
Stilbenes are some of the important phenolic compounds originating from plant families like
Vitaceae, Leguminaceae, Gnetaceae, and Dipterocarpaceae. Structurally, they have a C6 …

Chemistry and biology of resveratrol-derived natural products

MH Keylor, BS Matsuura, CRJ Stephenson - Chemical reviews, 2015 - ACS Publications
Since the dawn of the 20th century, the average life expectancy at birth has nearly doubled
due to advances in science and medicine. As medical records grew more reliable, it became …

Therapeutic potential of SphK1 inhibitors based on abnormal expression of SphK1 in inflammatory immune related-diseases

Y Bu, H Wu, R Deng, Y Wang - Frontiers in Pharmacology, 2021 - frontiersin.org
Sphingosine kinase 1 (SphK1) a key enzyme that catalyzes the conversion of sphingosine
(Sph) to sphingosine 1-phosphate (S1P), so as to maintain the dynamic balance of …

[HTML][HTML] Applications of Friedel–Crafts reactions in total synthesis of natural products

MM Heravi, V Zadsirjan, P Saedi, T Momeni - RSC advances, 2018 - pubs.rsc.org
Over the years, Friedel–Crafts (FC) reactions have been acknowledged as the most useful
and powerful synthetic tools for the construction of a special kind of carbon–carbon bond …

Comparative Analyses of Stilbenoids in Canes of Major Vitis vinifera L. Cultivars

C Lambert, T Richard, E Renouf, J Bisson… - Journal of agricultural …, 2013 - ACS Publications
Grapevine canes are rich in resveratrol and its complex derivatives. These compounds have
many biological activities and are needed mainly for health purposes. Canes, which are …

Structure-activity-relationship and mechanistic insights for anti-HIV natural products

R Kaur, P Sharma, GK Gupta, F Ntie-Kang, D Kumar - Molecules, 2020 - mdpi.com
Acquired Immunodeficiency Syndrome (AIDS), which chiefly originatesfroma retrovirus
named Human Immunodeficiency Virus (HIV), has impacted about 70 million people …

Resveratrol oligomers for the prevention and treatment of cancers

YQ Xue, JM Di, Y Luo, KJ Cheng… - … Medicine and Cellular …, 2014 - Wiley Online Library
Resveratrol (3, 4′, 5‐trihydroxystilbene) is a naturally derived phytoalexin stilbene isolated
from grapes and other plants, playing an important role in human health and is well known …

Scopoletin, a coumarin derivative compound isolated from Macaranga gigantifolia Merr

A Darmawan, S Kosela, LBS Kardono… - Journal of Applied …, 2012 - japsonline.com
Abstract Scopoletin (1), a coumarin derivative compound has been isolated from methanol
extract of Macaranga gigantifolia Merr. leaves using chromatography methods. Chemical …

Versatile Route to Benzoannulated Medium-Ring Carbocycles via Aryne Insertion into Cyclic 1, 3-Diketones: Application to a Synthesis of Radermachol

R Samineni, P Srihari, G Mehta - Organic letters, 2016 - ACS Publications
A general approach involving the insertion of in situ generated aryne into the C–C bond of
cyclic 1, 3-diketones for rapidly assembling functionalized benzo-fused medium ring …

Niosome-encapsulated balanocarpol: compound isolation, characterisation, and cytotoxicity evaluation against human breast and ovarian cancer cell lines

MA Obeid, SAS Gany, AI Gray, L Young, JO Igoli… - …, 2020 - iopscience.iop.org
Natural products have been successfully used to treat various ailments since ancient times
and currently several anticancer agents based on natural products are used as the main …