Importance Substance use disorders (SUDs) represent a pressing public health concern.
Combined behavioral and pharmacological interventions are considered best practices for …

Background Clinical guidelines recommend psychosocial interventions for cocaine and/or
amphetamine addiction as first-line treatment, but it is still unclear which intervention, if any …

Objective: Despite significant advances in psychosocial treatments for substance use
disorders, the relative success of these approaches has not been well documented. In this …

Background Despite its success with compliant or supervised patients, disulfiram has been a
controversial medication in the treatment of alcoholism. Often, study designs did not …

Objective: This meta-analysis examined 53 controlled trials of cognitive-behavioral treatment
(CBT) for adults diagnosed with alcohol-or illicit-drug-use disorders. The aims were to …

Background Alcohol dependence belongs to the globally leading health risk factors.
Therapeutic success of psychosocial programs for relapse prevention is moderate and could …

Dopamine is an important neuromodulator that exerts widespread effects on the central
nervous system (CNS) function. Disruption in dopaminergic neurotransmission can have …

The past three decades have been marked by tremendous progress in behavioral therapies
for drug abuse and dependence, as well as advances in the conceptualization of …

This comprehensive clinical handbook provides virtually everything needed to plan, deliver,
and evaluate effective treatment for persons with substance abuse problems and persistent …

Background Antisocial personality disorder (AsPD) is associated with poor mental health,
criminality, substance use and relationship difficulties. This review updates Gibbon 2010 …