Acute graft-versus-host disease

F Malard, E Holler, BM Sandmaier, H Huang… - Nature Reviews …, 2023 - nature.com
Acute graft-versus-host disease (GVHD) is a common immune complication that can occur
after allogeneic haematopoietic cell transplantation (alloHCT). Acute GVHD is a major …

Conditioning regimens for hematopoietic cell transplantation: one size does not fit all

B Gyurkocza, BM Sandmaier - Blood, The Journal of the …, 2014 - ashpublications.org
An essential component of allogeneic and autologous hematopoietic cell transplantation
(HCT) is the conditioning regimen administered before the hematopoietic cell infusion. Early …

Immunobiology of allogeneic hematopoietic stem cell transplantation

LA Welniak, BR Blazar, WJ Murphy - Annu. Rev. Immunol., 2007 - annualreviews.org
Allogeneic hematopoietic stem cell transplantation (HSCT) has evolved into an effective
adoptive cellular immunotherapy for the treatment of a number of cancers. The …

Allogeneic hematopoietic stem-cell transplantation for sickle cell disease

MM Hsieh, EM Kang, CD Fitzhugh… - … England Journal of …, 2009 - Mass Medical Soc
Background Myeloablative allogeneic hematopoietic stem-cell transplantation is curative in
children with sickle cell disease, but in adults the procedure is unduly toxic. Graft rejection …

Current and emerging strategies for the prevention of graft-versus-host disease

SW Choi, P Reddy - Nature reviews Clinical oncology, 2014 - nature.com
Graft-versus-host disease (GVHD) represents the most serious and challenging
complication of allogeneic haematopoietic stem-cell transplantation (HSCT). New insights …

Adenovirus infections following allogeneic stem cell transplantation: incidence and outcome in relation to graft manipulation, immunosuppression, and immune …

S Chakrabarti, V Mautner, H Osman… - Blood, The Journal …, 2002 - ashpublications.org
Adenovirus infections occur in 5% to 21% of patients following stem cell transplantation
(SCT), with an associated mortality of up to 50%. However, a lack of prospective studies has …

Tolerance and cancer: mechanisms of tumor evasion and strategies for breaking tolerance

MY Mapara, M Sykes - Journal of clinical oncology, 2004 - ascopubs.org
The development of malignant disease might be seen as a failure of immune surveillance.
However, not all tumors are naturally immunogenic, and even among those that are …

[HTML][HTML] Comparison of outcomes of HLA-matched related, unrelated, or HLA-haploidentical related hematopoietic cell transplantation following nonmyeloablative …

LM Burroughs, PV O'Donnell, BM Sandmaier… - Biology of blood and …, 2008 - Elsevier
We compared the outcome of nonmyeloablative allogeneic hematopoietic cell
transplantation (HCT) for patients with relapsed or refractory Hodgkin lymphoma (HL) based …

Allogeneic stem-cell transplantation as salvage therapy for patients with diffuse large B-cell non-Hodgkin's lymphoma relapsing after an autologous stem-cell …

RJW Van Kampen, C Canals, HC Schouten… - Journal of clinical …, 2011 - ascopubs.org
Purpose To analyze the outcome, including nonrelapse mortality (NRM), relapse rate (RR),
progression-free survival (PFS), and overall survival (OS), of patients with diffuse large B-cell …

Graft-versus-lymphoma effect in relapsed peripheral T-cell non-Hodgkin's lymphomas after reduced-intensity conditioning followed by allogeneic transplantation of …

P Corradini, A Dodero, F Zallio, D Caracciolo… - Journal of Clinical …, 2004 - ascopubs.org
Purpose Peripheral T-cell lymphomas (PTCLs) are a heterogeneous group of malignancies
characterized by a poor prognosis. We performed a pilot study to investigate the role of …