The skin is a complex organ that has devised numerous strategies, such as physical,
chemical, and microbiological barriers, to protect the host from external insults. In addition …

Fibronectin structure and composition regulate contextual cell signaling. Recent advances
have been made in understanding fibronectin and its role in tissue organization and repair …

Adult mammalian skin wounds heal by forming fibrotic scars. We report that full-thickness
injuries of reindeer antler skin (velvet) regenerate, whereas back skin forms fibrotic scar …

Wound healing is a largely unmet medical issue in trauma, burn, and diabetes. In this study,
a pullulan-based and nanoparticle-loaded smart microneedle patch is designed to release …

The morbidity, mortality, and burden of burn victims and patients with severe diabetic
wounds are still high, which leads to an extensively growing demand for novel treatments …

Fibrosis is a pathologic process characterized by the replacement of parenchymal tissue by
large amounts of extracellular matrix, which may lead to organ dysfunction and even death …

Large skin wounds pose a major clinical challenge. Scarcity of donor site and postsurgical
scarring contribute to the incomplete or partial loss of function and aesthetic concerns in skin …

BACKGROUND The human uterine endometrium undergoes significant remodeling and
regeneration on a rapid and repeated basis, after parturition, menstruation, and in some …

Cutaneous fibrosis results from suboptimal wound healing following significant tissue injury
such as severe burns, trauma, and major surgeries. Pathologic skin fibrosis results in scars …

Scars caused by skin injuries after burns, wounds, abrasions and operations have serious
physical and psychological effects on patients. In recent years, the research of scar free …