The relationship between obesity and cognitive health and decline

L Dye, NB Boyle, C Champ, C Lawton - Proceedings of the nutrition …, 2017 - cambridge.org
The relationship between obesity and cognitive impairment is important given the globally
ageing population in whom cognitive decline and neurodegenerative disorders will carry …

Compromised white matter integrity in obesity

S Kullmann, F Schweizer, R Veit, A Fritsche… - Obesity …, 2015 - Wiley Online Library
Obesity is associated with both structural and functional changes of the central nervous
system. While gray matter alterations in obesity point to a consistent reduction with …

[HTML][HTML] Obesity associated with increased brain age from midlife

L Ronan, AF Alexander-Bloch, K Wagstyl, S Farooqi… - Neurobiology of …, 2016 - Elsevier
Common mechanisms in aging and obesity are hypothesized to increase susceptibility to
neurodegeneration, however, direct evidence in support of this hypothesis is lacking. We …

[HTML][HTML] Specific white matter tissue microstructure changes associated with obesity

S Kullmann, MF Callaghan, M Heni, N Weiskopf… - Neuroimage, 2016 - Elsevier
Obesity-related structural brain alterations point to a consistent reduction in gray matter with
increasing body mass index (BMI) but changes in white matter have proven to be more …

White matter microstructure and cognitive decline in metabolic syndrome: a review of diffusion tensor imaging

FJ Alfaro, A Gavrieli, P Saade-Lemus, VA Lioutas… - Metabolism, 2018 - Elsevier
Metabolic syndrome is a cluster of cardiovascular risk factors defined by the presence of
abdominal obesity, glucose intolerance, hypertension and/or dyslipidemia. It is a major …

Neurocognitive effects of obesity and bariatric surgery

MB Spitznagel, M Hawkins, M Alosco… - European Eating …, 2015 - Wiley Online Library
This review paper will discuss the recent literature examining the relationship between
obesity and neurocognitive outcomes, with a particular focus on cognitive changes after …

Normal-appearing cerebral white matter in healthy adults: mean change over 2 years and individual differences in change

AR Bender, N Raz - Neurobiology of aging, 2015 - Elsevier
Diffusion tensor imaging studies show age-related differences in cerebral white matter (WM).
However, few have studied WM changes over time, and none evaluated individual …

Brain structure and cognitive correlates of body mass index in healthy older adults

JD Bolzenius, DH Laidlaw, RP Cabeen… - Behavioural Brain …, 2015 - Elsevier
Obesity, commonly measured with body mass index (BMI), is associated with numerous
deleterious health conditions including alterations in brain integrity related to advanced age …

Inflammatory Pathways in Overweight and Obese Persons as a Potential Mechanism for Cognitive Impairment and Earlier Onset Alzeihmer's Dementia in the General …

AD Costache, BE Ignat, C Grosu, A Mastaleru… - Biomedicines, 2023 - mdpi.com
The overweight status or obesity can be confirmed through classical methods such as the
body mass index (BMI) and the waist-to-hip ratio (WHR). Apart from metabolic issues such …

Improved serum leptin and ghrelin following bariatric surgery predict better postoperative cognitive function

ML Alosco, MB Spitznagel, G Strain… - Journal of clinical …, 2015 - synapse.koreamed.org
Background and Purpose Bariatric surgery is associated with improved cognitive function,
but the mechanisms underlying these gains remain poorly understood. Disturbed leptin and …