A review of the common neurodegenerative disorders: current therapeutic approaches and the potential role of nanotherapeutics
Neurodegenerative disorders are primarily characterized by neuron loss. The most common
neurodegenerative disorders include Alzheimer's and Parkinson's disease. Although there …
neurodegenerative disorders include Alzheimer's and Parkinson's disease. Although there …
[HTML][HTML] A review of biological targets and therapeutic approaches in the management of triple-negative breast cancer
Background Triple-negative breast cancer (TNBC) is a heterogeneous, aggressive
phenotype of breast cancer with associated chemoresistance. The development of chemo-or …
phenotype of breast cancer with associated chemoresistance. The development of chemo-or …
Multifunctionalized cationic chitosan polymeric micelles polyplexed with pvgf for noninvasive delivery to the mouse brain through the intranasal route for developing …
A Gothwal, RNL Lamptey, J Singh - Molecular Pharmaceutics, 2023 - ACS Publications
Multifunctionalized Chitosan-based polymeric micelles were used to deliver pVGF to the
brain. VGF (non-acronymic) plays significant roles in neurogenesis and learning as well as …
brain. VGF (non-acronymic) plays significant roles in neurogenesis and learning as well as …
Synthesis and characterization of fatty acid grafted chitosan polymeric micelles for improved gene delivery of VGF to the brain through intranasal route
Multifunctional fatty acid grafted polymeric micelles are an effective and promising approach
for drug and gene delivery to the brain. An alternative approach to bypass the blood–brain …
for drug and gene delivery to the brain. An alternative approach to bypass the blood–brain …
Neurogenic hypertension, the blood–brain barrier, and the potential role of targeted nanotherapeutics
RNL Lamptey, C Sun, B Layek, J Singh - International Journal of …, 2023 - mdpi.com
Hypertension is a major health concern globally. Elevated blood pressure, initiated and
maintained by the brain, is defined as neurogenic hypertension (NH), which accounts for …
maintained by the brain, is defined as neurogenic hypertension (NH), which accounts for …
Brain-targeted delivery of losartan through functionalized liposomal nanoparticles for management of neurogenic hypertension
RNL Lamptey, C Sun, J Singh - International journal of pharmaceutics, 2023 - Elsevier
There is mounting experimental evidence that blocking angiotensin receptor type 1 activity
can prevent the occurrence of hypertension in spontaneously hypertensive rats. Studies …
can prevent the occurrence of hypertension in spontaneously hypertensive rats. Studies …