The differential diagnosis of parkinsonian syndromes is considered one of the most
challenging in neurology and error rates in the clinical diagnosis can be high even at …

Relatively subtle cognitive disturbances may be present from the initial stages of Parkinson's
disease (PD) that progress in many patients to a more severe cognitive impairment and …

One objective of modern neuroimaging is to identify markers that can aid in diagnosis,
disease progression monitoring and long-term drug impact analysis. In this study, Parkinson …

Background Parkinson's disease (PD) is a chronic neurodegenerative disorder
characterized by bradykinesia, tremor, and rigidity among other symptoms. With a 70 …

Cognitive defects associated with cortical pathology may be a marker of dementia in
Parkinson's disease (PD). There is a need to improve the diagnostic criteria of PD dementia …

Background The genesis of severe fatigue and disability in people following acute pathogen
invasion involves the activation of Toll-like receptors followed by the upregulation of …

Previous studies have shown greater atrophy in grey and white matter of various brain
regions in patients with Parkinson's disease with mild cognitive impairment than in those …

Parkinson's disease (PD) is the most common neurological disorder, after Alzheimer's
disease, and is characterized by a long prodromal stage lasting up to 20 years. As age is a …

Parkinson's disease (PD) is the second most common neurodegenerative disease after
Alzheimer's disease (AD). It is characterized by a progressive loss of dopaminergic neurons …

Cognitive decline is one of the most frequent and disabling nonmotor features of Parkinson's
disease. Around 30% of patients with Parkinson's disease experience mild cognitive …