State-of-the-art and potential of experimental microdosimetry in ion-beam therapy

G Magrin, H Palmans, M Stock, D Georg - Radiotherapy and Oncology, 2023 - Elsevier
In radiotherapy, radiation-quality should be an expression of the biological and physical
characteristics of ionizing radiation such as spatial distribution of ionization or energy …

Nanodosimetry, the metrological tool for connecting radiation physics with radiation biology

B Grosswendt - Radiation protection dosimetry, 2006 - academic.oup.com
It is generally accepted that the early damage to genes or cells by ionising radiation starts
with the early damage to segments of the DNA, at least, to the greater part. This damage is …

A semiconductor radiation imaging pixel detector for space radiation dosimetry

M Kroupa, A Bahadori, T Campbell-Ricketts… - Life sciences in space …, 2015 - Elsevier
Progress in the development of high-performance semiconductor radiation imaging pixel
detectors based on technologies developed for use in high-energy physics applications has …

ICRU Report 98, Stochastic Nature of Radiation Interactions: Microdosimetry

LA Braby, V Conte, M Dingfelder… - Journal of the …, 2023 - journals.sagepub.com
ICRU Report 98, Stochastic Nature of Radiation Interactions: Microdosimetry - LA Braby, V.
Conte, M. Dingfelder, DT Goodhead, LS Pinsky, AB Rosenfeld, T. Sato, AJ Waker, S. Guatelli …

Diamond based integrated detection system for dosimetric and microdosimetric characterization of radiotherapy ion beams

C Verona, S Barna, D Georg, Y Hamad… - Medical …, 2024 - Wiley Online Library
Background Ion beam therapy allows for a substantial sparing of normal tissues and higher
biological efficacy. Synthetic single crystal diamond is a very good material to produce high …

A method to convert spectra from slab microdosimeters in therapeutic ion-beams to the spectra referring to microdosimeters of different shapes and material

G Magrin - Physics in Medicine & Biology, 2018 - iopscience.iop.org
Experimental studies of microdosimetry in therapeutic ion beams have been performed
using several detectors. The differences among the microdosimeters lie on the shapes, the …

Gas amplification and ionization coefficients in isobutane and argon–isobutane mixtures at low gas pressures

IK Bronić, B Grosswendt - Nuclear Instruments and Methods in Physics …, 1998 - Elsevier
Measurements of the mean gas amplification factor in isobutane and in argon–isobutane
mixtures are performed at total gas pressures of 10, 20, 30, 60 and 90 kPa over a range of …

Monte Carlo design study for thick gas electron multiplier-based multi-element microdosimetric detector

Z Anjomani, AR Hanu, WV Prestwich… - Nuclear Instruments and …, 2014 - Elsevier
To accomplish enhanced neutron dose response with high detection efficiency, a set of multi-
element microdosimetric detectors were designed using THick Gas Electron Multiplier …

Energy-loss straggling and delta-ray escape in solid-state microdosimeters used in ion-beam therapy

G Magrin, S Barna, C Meouchi, A Rosenfeld… - Journal of Nuclear …, 2022 - mdpi.com
Microdosimetry is increasingly adopted in the characterization of proton and carbon ion
beams used in cancer therapy. Spectra and mean values of lineal energy calculated in …

Design of a new tissue-equivalent proportional counter based on a gas electron multiplier

M Farahmand, AJJ Bos, J Huizenga, L De Nardo… - Nuclear Instruments and …, 2003 - Elsevier
By employing a Gas Electron Multiplier a new type of mini multi-element Tissue-Equivalent
Proportional Counter (TEPC) has been designed and constructed. In this paper, we describe …