Lipid metabolic reprogramming in tumor microenvironment: from mechanisms to therapeutics

HR Jin, J Wang, ZJ Wang, MJ Xi, BH Xia… - Journal of Hematology & …, 2023 - Springer
Lipid metabolic reprogramming is an emerging hallmark of cancer. In order to sustain
uncontrolled proliferation and survive in unfavorable environments that lack oxygen and …

Applying machine learning algorithms to develop a survival prediction model for lung adenocarcinoma based on genes related to fatty acid metabolism

D Cong, Y Zhao, W Zhang, J Li, Y Bai - Frontiers in Pharmacology, 2023 - frontiersin.org
Background: The progression of lung adenocarcinoma (LUAD) may be related to abnormal
fatty acid metabolism (FAM). The present study investigated the relationship between FAM …

The Diagnostic Value of ACSL1, ACSL4, and ACSL5 and the Clinical Potential of an ACSL Inhibitor in Non-Small-Cell Lung Cancer

Y Ma, M Nenkov, A Berndt, M Abubrig, M Schmidt… - Cancers, 2024 - mdpi.com
Simple Summary Long-chain Acyl-CoA synthetase (ACSL) family members are involved in
long-chain fatty acid activation, a crucial step for cells to utilize fatty acids (FAs) in the …