S100 is a broad subfamily of low-molecular weight calcium-binding proteins (9–14 kDa) with
structural similarity and functional discrepancy. It is required for inflammation and cellular …

Abstract Juvenile Idiopathic Arthritis (JIA) represents a diverse group of chronic inflammatory
conditions that begin in childhood or adolescence and continue into adulthood, with varying …

Background Early diagnosis and treatment of juvenile idiopathic arthritis (JIA) with
conventional and biologic disease-modifying anti-rheumatic drugs have vastly improved …

Autoimmune and auto-inflammatory diseases in children are causing chronic inflammation,
organ damage, and pain. Although several options for treatment are nowadays available a …

Long-term inflammation and impaired angiogenesis are thought to be the causes of delayed
healing or nonhealing of diabetic wounds. S100A12 is an essential pro-inflammatory factor …

Objectives To investigate the ability of high-sensitivity C-reactive protein (hsCRP) and
S100A12 to serve as predictive biomarkers of successful drug withdrawal in children with …

There is an urgent need to identify biomarkers for diagnosis and disease activity monitoring
in rheumatoid arthritis (RA). We leveraged publicly available microarray gene expression …

Background Our aim was attempting to find proteins involved in the pain process and
correlating with pain but not degree of inflammation in children with juvenile idiopathic …

The aims of treating juvenile idiopathic arthritis are to elicit treatment response toward
remission, while preventing future flares. Understanding patient and disease characteristics …

Introduction Genome wide association studies (GWAS) have identified multiple regions that
confer genetic risk for the polyarticular/oligoarticular forms of juvenile idiopathic arthritis …