Neospora caninum–how close are we to development of an efficacious vaccine that prevents abortion in cattle?

MP Reichel, JT Ellis - International journal for parasitology, 2009 - Elsevier
Neospora caninum is a protozoan parasite that causes abortion in cattle around the world.
Although the clinical signs of disease in both dogs and cattle have now been recognised for …

Vaccines against neosporosis: what can we learn from the past studies?

T Monney, A Hemphill - Experimental parasitology, 2014 - Elsevier
Neospora caninum is an intracellular apicomplexan parasite, which is a leading cause of
abortion in cattle; thus neosporosis represents an important veterinary health problem and is …

[图书][B] Neosporosis in animals

JP Dubey, A Hemphill, R Calero-Bernal, G Schares - 2017 - taylorfrancis.com
Key features: Written by the scientist who named this parasite and was the first to set up
proper diagnostic techniques Serves as the first ever book to provide information on the …

Canine neosporosis: perspectives on pathogenesis and management

RC Silva, GP Machado - Veterinary Medicine: Research and …, 2016 - Taylor & Francis
Canine neosporosis is a worldwide disease caused by the obligate intracellular parasite
protozoan Neospora caninum, manifesting mainly neurological symptoms. N. caninum has a …

Approaches for the vaccination and treatment of Neospora caninum infections in mice and ruminant models

A Hemphill, A Aguado-Martinez, J Mueller - Parasitology, 2016 - cambridge.org
Neospora caninum is a leading cause of abortion in cattle, and is thus an important
veterinary health problem of high economic significance. Vaccination has been considered …

[PDF][PDF] Proteins mediating the Neospora caninum-host cell interaction as targets for vaccination

A Hemphill, K Debache, T Monney, M Schorer… - Front Biosci (Elite …, 2013 - researchgate.net
Neospora caninum and neosporosis 3. Host cell adhesion/invasion by N. caninum and
related apicomplexan parasites 3.1. Initial adhesion is mediated by surface antigens (SAGs) …

Vaccines against a Major Cause of Abortion in Cattle, Neospora caninum Infection

T Monney, K Debache, A Hemphill - Animals, 2011 - mdpi.com
Simple Summary We review the efforts to develop a vaccine against neosporosis, caused by
the apicomplexan parasite Neospora caninum. Vertical transmission is the main mode of …

Comparative host–parasite relationships in ovine toxoplasmosis and bovine neosporosis and strategies for vaccination

EA Innes, PM Bartley, SW Maley, SE Wright, D Buxton - Vaccine, 2007 - Elsevier
Toxoplasma gondii and Neospora caninum are important causes of reproductive loss in
ruminant species worldwide. Both parasites cause disease during pregnancy that may result …

Evaluation of recombinant proteins of Neospora caninum as vaccine candidates (in a mouse model)

J Ellis, C Miller, H Quinn, C Ryce, MP Reichel - Vaccine, 2008 - Elsevier
Abortion, resulting from infections by the parasite Neospora caninum, is a major cause of
economic loss to both the dairy and beef industries of cattle-producing countries of the …

The Impact of BKI-1294 Therapy in Mice Infected With the Apicomplexan Parasite Neospora caninum and Re-infected During Pregnancy

P Winzer, D Imhof, N Anghel, D Ritler… - Frontiers in veterinary …, 2020 - frontiersin.org
Exposure of Neospora caninum tachyzoites to BKI-1294 in vitro results in the formation of
long-lived multinucleated complexes (MNCs). However, in vivo treatment of BALB/c mice …