Deubiquitinating enzymes (DUBs) are proteases that process ubiquitin or ubiquitin-like gene
products, reverse the modification of proteins by a single ubiquitin (-like) protein, and …

Modification of proteins by the covalent attachment of ubiquitin is a key regulatory
mechanism of many cellular processes including protein degradation by the 26S pro …

The ubiquitin-specific processing protease (UBP) family of deubiquitinating enzymes plays
an essential role in numerous cellular processes. HAUSP, a representative UBP, specifically …

Proteases perform important roles in multiple biological and pathological processes. The
availability of the rat genome sequence has facilitated the analysis of the complete protease …

The transcription factor nuclear factor (erythroid-derived 2)-like 2 (NRF2) is one of the master
regulators that control hundreds of genes containing antioxidant response elements (AREs) …

Ubiquitin‐specific proteases (UBPs) are a highly conserved family of proteins in eukaryotes,
and play critical roles in protein de‐ubiquitination. Here we report a systematic genetic and …

It has become apparent that ubiquitination plays a critical role in cell survival and cell death.
In addition, deubiquitinating enzymes (DUBs) have been determined to be highly important …

Deubiquitinating enzymes regulate a number of cellular mechanisms including pre-
implantation, growth and differentiation, oncogenesis, cell cycle progression, transcriptional …

Previous studies have identified the DUB family of cytokine-regulated murine
deubiquitinating enzymes, which play a role in the control of cell proliferation and survival …

Deubiquitinating enzymes are now emerging as potential therapeutic targets that control
many cellular processes, but few have been demonstrated to control cell motility. Here, we …