Development and functional diversification of cortical interneurons

L Lim, D Mi, A Llorca, O Marín - Neuron, 2018 - cell.com
In the cerebral cortex, GABAergic interneurons have evolved as a highly heterogeneous
collection of cell types that are characterized by their unique spatial and temporal …

Hippocampal GABAergic inhibitory interneurons

KA Pelkey, R Chittajallu, MT Craig… - Physiological …, 2017 - journals.physiology.org
In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

Developmental diversification of cortical inhibitory interneurons

C Mayer, C Hafemeister, RC Bandler, R Machold… - Nature, 2018 - nature.com
Diverse subsets of cortical interneurons have vital roles in higher-order brain functions. To
investigate how this diversity is generated, here we used single-cell RNA sequencing to …

Interneuron origin and molecular diversity in the human fetal brain

Y Yu, Z Zeng, D Xie, R Chen, Y Sha, S Huang… - Nature …, 2021 - nature.com
Precise generation of excitatory neurons and inhibitory interneurons is crucial for proper
formation and function of neural circuits in the mammalian brain. Because of the size and …

Cortical interneuron development: a tale of time and space

JS Hu, D Vogt, M Sandberg, JL Rubenstein - Development, 2017 - journals.biologists.com
Cortical interneurons are a diverse group of neurons that project locally and are crucial for
regulating information processing and flow throughout the cortex. Recent studies in mice …

Origin, development, and synaptogenesis of cortical interneurons

A Llorca, R Deogracias - Frontiers in Neuroscience, 2022 - frontiersin.org
The mammalian cerebral cortex represents one of the most recent and astonishing
inventions of nature, responsible of a large diversity of functions that range from sensory …

Cortical interneuron specification: the juncture of genes, time and geometry

RC Bandler, C Mayer, G Fishell - Current opinion in neurobiology, 2017 - Elsevier
Highlights•The GEs produce many types of GABAergic projection neurons and a majority of
GABAergic interneurons.•Spatial origin, birthdate, and mode of division influence …

From progenitors to progeny: shaping striatal circuit development and function

R Knowles, N Dehorter, T Ellender - Journal of Neuroscience, 2021 - Soc Neuroscience
Understanding how neurons of the striatum are formed and integrate into complex synaptic
circuits is essential to provide insight into striatal function in health and disease. In this …

Local thyroid hormone action in brain development

A Alcaide Martin, S Mayerl - International Journal of Molecular Sciences, 2023 - mdpi.com
Proper brain development essentially depends on the timed availability of sufficient amounts
of thyroid hormone (TH). This, in turn, necessitates a tightly regulated expression of TH …

Beyond axon guidance: roles of slit-robo signaling in neocortical formation

Y Gonda, T Namba, C Hanashima - Frontiers in cell and …, 2020 - frontiersin.org
The formation of the neocortex relies on intracellular and extracellular signaling molecules
that are involved in the sequential steps of corticogenesis, ranging from the proliferation and …