Age-related hearing loss, or presbycusis, is a common cause of hearing loss in elderly
people worldwide. It typically presents as progressive, irreversible, and usually affects the …

Loss of synapses between spiral ganglion neurons and inner hair cells (IHC synaptopathy)
leads to an auditory neuropathy called hidden hearing loss (HHL) characterized by normal …

Background Age-related hearing loss (ARHL)—also termed presbycusis—is prevalent
among older adults, leading to a range of issues. Although considerable progress in the …

Quantifying the survival patterns of spiral ganglion cells (SGCs), the cell bodies of auditory-
nerve fibers, is critical to studies of sensorineural hearing loss, especially in human temporal …

Sensorineural hearing loss is caused by damage to sensory hair cells and/or spiral ganglion
neurons. In non-mammalian species, hair cell regeneration after damage is observed, even …

The disruption of the synaptic connection between the sensory inner hair cells (IHCs) and
the auditory nerve fiber terminals of the type I spiral ganglion neurons (SGN) has been …

Auditory neuropathy (AN) is an under-recognized form of hearing loss characterized by
lesions in inner hair cells (IHCs), ribbon synapses and spiral ganglion neurons (SGNs). The …

Background Age-related hearing loss (ARHL) is a common sensory disorder with significant
public health implications. However, few effective treatment options are available …

To study key proteins associated with changes in synaptic transmission in the spiral
ganglion in tinnitus, we build three gene lists from the GeneCard database: 1. Perception of …

Loss of sensory hair cells from exposure to certain licit drugs, such as aminoglycoside
antibiotics, can result in permanent hearing damage. Exogenous application of the …