Beneficial health effects of glucosinolates-derived isothiocyanates on cardiovascular and neurodegenerative diseases

RM Kamal, AF Abdull Razis, NS Mohd Sukri… - Molecules, 2022 - mdpi.com
Neurodegenerative diseases (NDDs) and cardiovascular diseases (CVDs) are illnesses that
affect the nervous system and heart, all of which are vital to the human body. To maintain …

[HTML][HTML] Reducing anastomotic leak in colorectal surgery: The old dogmas and the new challenges

J Meyer, S Naiken, N Christou, E Liot… - World journal of …, 2019 - ncbi.nlm.nih.gov
Anastomotic leak (AL) constitutes a significant issue in colorectal surgery, and its incidence
has remained stable over the last years. The use of intra-abdominal drain or the use of …

Mechanisms underlying biological effects of cruciferous glucosinolate-derived isothiocyanates/indoles: a focus on metabolic syndrome

M Esteve - Frontiers in Nutrition, 2020 - frontiersin.org
An inverse correlation between vegetable consumption and the incidence of cancer has
long been described. This protective effect is stronger when cruciferous vegetables are …

[HTML][HTML] Allyl isothiocyanate ameliorates lipid accumulation and inflammation in nonalcoholic fatty liver disease via the Sirt1/AMPK and NF-κB signaling pathways

CX Li, JG Gao, XY Wan, Y Chen, CF Xu… - World journal of …, 2019 - ncbi.nlm.nih.gov
BACKGROUND Allyl isothiocyanate (AITC), a classic anti-inflammatory and antitumorigenic
agent, was recently identified as a potential treatment for obesity and insulin resistance …

Neuroprotective and anti-inflammatory activities of allyl isothiocyanate through attenuation of JNK/NF-κB/TNF-α signaling

L Subedi, R Venkatesan, SY Kim - International journal of molecular …, 2017 - mdpi.com
Allyl isothiocyanate (AITC), present in Wasabia japonica (wasabi), is an aliphatic
isothiocyanate derived from the precursor sinigrin, which is a glucosinolate present in …

[HTML][HTML] Thermosensitive smart hydrogel of PEITC ameliorates the therapeutic efficacy in rheumatoid arthritis

P Haloi, S Chawla, VB Konkimalla - European Journal of Pharmaceutical …, 2023 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune condition that accompanies chronic
inflammation of joints with limited therapeutic options. Phenethyl isothiocyanate (PEITC), a …

Isothiocyanates from Brassica Vegetables—Effects of Processing, Cooking, Mastication, and Digestion

T Oliviero, R Verkerk, M Dekker - Molecular nutrition & food …, 2018 - Wiley Online Library
The formation of health‐beneficial isothiocyanates (ITCs) from glucosinolates depends on a
wide variety of plant‐intrinsic factors (eg, concentration of glucosinolates, activity of …

Molecular mechanisms of the anti-cancer effects of isothiocyanates from cruciferous vegetables in bladder cancer

T Mastuo, Y Miyata, T Yuno, Y Mukae, A Otsubo… - Molecules, 2020 - mdpi.com
Bladder cancer (BC) is a representative of urological cancer with a high recurrence and
metastasis potential. Currently, cisplatin-based chemotherapy and immune checkpoint …

Metabolic and biotransformation effects on dietary glucosinolates, their bioavailability, catabolism and biological effects in different organisms

ZT Shakour, NG Shehab, AS Gomaa… - Biotechnology …, 2022 - Elsevier
Glucosinolate-producing plants have long been recognized for both their distinctive benefits
to human nutrition and their resistance traits against pathogens and herbivores. Despite the …

Cruciferous vegetables: rationale for exploring potential salutary effects of sulforaphane-rich foods in patients with chronic kidney disease

LFMF Cardozo, LA Alvarenga, M Ribeiro, L Dai… - Nutrition …, 2021 - academic.oup.com
Sulforaphane (SFN) is a sulfur-containing isothiocyanate found in cruciferous vegetables
(Brassicaceae) and a well-known activator of nuclear factor-erythroid 2-related factor 2 …