Frailty, a critical intermediate status of the aging process that is at increased risk for negative
health-related events, includes physical, cognitive, and psychosocial domains or …

The immune system is the central regulator of tissue homeostasis, ensuring tissue
regeneration and protection against both pathogens and the neoformation of cancer cells. Its …

Incidence rates of cognitive impairment and dementia are rising with the ageing population.
Meanwhile, the limited success of current treatments has led to a search for early markers of …

Background and Purpose: Frailty has been recognized as a medical syndrome
characterized by decreased physiological reserve and vulnerability to poor resolution of …

Frailty is a complex and heterogeneous clinical syndrome. Cognitive frailty has been
considered as a subtype of frailty. In this study, we refine the definition of cognitive frailty …

Background One of the major threats looming over the growing older population is frailty. It is
a distinctive health state characterised by increased vulnerability to internal and external …

Um estudo foi planejado para identificar condições de fragilidade em relação a variáveis
sociodemográficas, de saúde, cognição, funcionalidade e psicossociais em idosos …

Age-related hearing impairment (ARHI, also known as presbycusis) is potentially a
reversible risk factor for dementia and Alzheimer disease (AD). Social isolation, loneliness …

Background/Aim: Current evidence in the literature supports associations between frailty,
cognitive impairment, and dementia. The study aim was to describe the risk of cognitive …

Frail, older patients pose a challenge to the primary care physician who may often feel
overwhelmed by their complex presentation and tenuous health status. At the same time …