Glutamatergic neurons of the mammalian cerebral cortex originate from radial glia (RG)
progenitors in the ventricular zone (VZ). During corticogenesis, neuroblasts migrate toward …

In mammals, excitatory cortical neurons develop from the proliferative epithelium and
progenitor cells in the ventricular zone and subventricular zone, and migrate radially to the …

Metastases arise from rare cancer cells that successfully adapt to the diverse
microenvironments encountered during dissemination through the bloodstream and …

While several major classes of neocortical neural precursor cells have been identified, the
lineal relationships and molecular profiles of these cells are still largely unknown …

Transcriptional mechanisms mediated by the binding of transcription factors (TFs) to cis-
acting regulatory elements (CREs) in DNA play crucial roles in directing gene expression …

Accumulating evidence suggests that many brain diseases are associated with defects in
neuronal migration, suggesting that this step of neurogenesis is critical for brain …

The phenotype of patients with a chromosome 1q43q44 microdeletion (OMIM; 612337) is
characterized by intellectual disability with no or very limited speech, microcephaly, growth …

Coordinated migration of newly-born neurons to their target territories is essential for correct
neuronal circuit assembly in the developing brain. Although a cohort of signaling pathways …

In utero electroporation (IUE) is a technique developed in the early 2000s to transfect the
neurons and neural progenitors of embryonic brains, thus enabling continued development …

Glioblastoma (GBM) comprises distinct subtypes characterized by their molecular profile.
Mesenchymal identity in GBM has been associated with a comparatively unfavorable …