Forces play a pivotal role in life, and the response of live systems to forces requires
molecules and molecular interactions with adequate properties to counteract both in a …

Although protein-folding studies began several decades ago, it is only recently that the tools
to analyze protein folding at the single-molecule level have been developed. Advances in …

Single-molecule force spectroscopy with the atomic force microscope provides molecular
level insights into protein function, allowing researchers to reconstruct energy landscapes …

Naturally occurring elastomeric proteins function as molecular springs in their biological
settings and show mechanical properties that underlie the elasticity of natural adhesives …

Elastomeric proteins act as the essential functional units in a wide variety of biomechanical
machinery and serve as the basic building blocks for biological materials that exhibit superb …

It is recognized that shear topology of two directly connected force-bearing terminal β-
strands is a common feature among the vast majority of mechanically stable proteins known …

Protein–ligand interactions, including protein–protein interactions, are ubiquitously essential
in biological processes and also have important applications in biotechnology. A wide range …

The activity of proteins and their complexes often involves the conversion of chemical
energy (stored or supplied) into mechanical work through conformational changes …

PEX1 and PEX6 are two members of the ATPases associated with diverse cellular activities
(AAA) family and the core components of the receptor export module of the peroxisomal …

The Sec translocon moves proteins across lipid bilayers in all cells. The Sec channel
enables passage of unfolded proteins through the bacterial plasma membrane, driven by …