Immunobiology of cervix ripening

SM Yellon - Frontiers in Immunology, 2020 - frontiersin.org
The cervix is the essential gatekeeper for birth. Incomplete cervix remodeling contributes to
problems with delivery at or post-term while preterm birth is a major factor in perinatal …

[HTML][HTML] Natural products in digestive tract tumors metabolism: Functional and application prospects

P Xing, Y Zhong, X Cui, Z Liu, X Wu - Pharmacological Research, 2023 - Elsevier
Digestive tract diseases are presently the hotspot of clinical diagnosis and treatment, and
the incidence of digestive tract tumor is increasing annually. Surgery remains the main …

Mimicking partial to total placental insufficiency in a rabbit model of cerebral palsy

Z Shi, K Luo, S Jani, M February… - Journal of …, 2022 - Wiley Online Library
All placental abruptions begin as partial abruptions, which sometimes manifest as fetal
bradycardia. The progression from partial to total abruption was mimicked by a new rabbit …

Effects of inflammatory and anti-inflammatory environments on the macrophage mitochondrial function

D Ji, J Yin, D Li, C Zhu, J Ye, Y Pan - Scientific Reports, 2020 - nature.com
Mitochondrial response to inflammation is crucial in the metabolic adaptation to infection.
This study aimed to explore the mitochondrial response under inflammatory and anti …

[HTML][HTML] Neuronal vulnerability to fetal hypoxia-reoxygenation injury and motor deficit development relies on regional brain tetrahydrobiopterin levels

J Vasquez-Vivar, Z Shi, JW Jeong, K Luo, A Sharma… - Redox Biology, 2020 - Elsevier
Hypertonia is pathognomonic of cerebral palsy (CP), often caused by brain injury before
birth. To understand the early driving events of hypertonia, we utilized magnetic resonance …

Microbiota signals during the neonatal period forge life-long immune responses

B Phillips-Farfán, F Gómez-Chávez… - International Journal of …, 2021 - mdpi.com
The microbiota regulates immunological development during early human life, with long-
term effects on health and disease. Microbial products include short-chain fatty acids …

Locomotion is impacted differently according to the perinatal brain injury model: Meta-analysis of preclinical studies with implications for cerebral palsy

S da Conceição Pereira, R Manhães-de-Castro… - Journal of Neuroscience …, 2021 - Elsevier
Background Different approaches to reproduce cerebral palsy (CP) in animals, contribute to
the knowledge of the pathophysiological mechanism of this disease and provide a basis for …

[Retracted] PSMB5 Alleviates Ulcerative Colitis by Inhibiting ROS‐Dependent NLRP3 Inflammasome‐Mediated Pyroptosis

L Han, Y Hao, X Wu, D Hu - Disease Markers, 2022 - Wiley Online Library
Ulcerative colitis (UC) is a chronic inflammatory disease. Intestinal mucosal injury is a
significant factor in UC. Pyroptosis is a kind of programmed cell death induced by …

Neonatal resveratrol treatment in cerebral palsy model recovers neurodevelopment impairments by restoring the skeletal muscle morphology and decreases …

S da Conceição Pereira, R Manhães-de-Castro… - Experimental …, 2024 - Elsevier
Cerebral Palsy (CP) is the main motor disorder in childhood resulting from damage to the
developing brain. Treatment perspectives are required to reverse the primary damage …

Acute hypobaric hypoxia exposure causes neurobehavioral impairments in rats: Role of brain catecholamines and tetrahydrobiopterin alterations

M Bhattacharjee, S Manoharan, UM Deshetty… - Neurochemical …, 2023 - Springer
Hypoxia is a state in which the body or a specific part of the body is deprived of adequate
oxygen supply at the tissue level. Sojourners involved in different activities at high altitudes …