Selenium in human health and gut microflora: bioavailability of selenocompounds and relationship with diseases

RLU Ferreira, KCM Sena-Evangelista… - Frontiers in …, 2021 - frontiersin.org
This review covers current knowledge of selenium in the dietary intake, its bioavailability,
metabolism, functions, biomarkers, supplementation and toxicity, as well as its relationship …

Selenium: an element for life

LH Duntas, S Benvenga - Endocrine, 2015 - Springer
This review aims to illustrate the importance of selenium (Se) for maintenance of overall
health, especially for the thyroid, immunity, and homeostasis. Furthermore, it outlines the …

Selenium and human health: witnessing a Copernican revolution?

E Jablonska, M Vinceti - … of Environmental Science and Health, Part …, 2015 - Taylor & Francis
In humans, selenium was hypothesized to lower the risk of several chronic diseases, mainly
due to the antioxidant activity of selenium-containing proteins. Recent epidemiologic and …

Selenium status: Its interactions with dietary mercury exposure and implications in human health

U Tinggi, AV Perkins - Nutrients, 2022 - mdpi.com
Selenium is an essential trace element in humans and animals and its role in selenoprotein
and enzyme antioxidant activity is well documented. Food is the principal source of …

The role of the thioredoxin/thioredoxin reductase system in the metabolic syndrome: towards a possible prognostic marker?

AA Tinkov, G Bjørklund, AV Skalny, A Holmgren… - Cellular and Molecular …, 2018 - Springer
Mammalian thioredoxin reductase (TrxR) is a selenoprotein with three existing isoenzymes
(TrxR1, TrxR2, and TrxR3), which is found primarily intracellularly but also in extracellular …

Optimising selenium for modulation of cancer treatments

SO Evans, PF Khairuddin, MB Jameson - Anticancer research, 2017 - ar.iiarjournals.org
Selenium is an essential trace element involved in many biological processes that are
mediated through, at least, 25 selenoproteins expressed in humans. Extensive study of …

[HTML][HTML] Selenium-enriched foods are more effective at increasing glutathione peroxidase (GPx) activity compared with selenomethionine: A meta-analysis

EN Bermingham, JE Hesketh, BR Sinclair, JP Koolaard… - Nutrients, 2014 - mdpi.com
Nutrients | Free Full-Text | Selenium-Enriched Foods Are More Effective at Increasing
Glutathione Peroxidase (GPx) Activity Compared with Selenomethionine: A Meta-Analysis Next …

Improved cardiovascular health by supplementation with selenium and coenzyme Q10: applying structural equation modelling (SEM) to clinical outcomes and …

U Alehagen, P Johansson, E Svensson… - European Journal of …, 2022 - Springer
Purpose Selenium and coenzyme Q10 have synergistic antioxidant functions. In a four-year
supplemental trial in elderly Swedes with a low selenium status, we found improved cardiac …

Comparative effects of two different forms of selenium on oxidative stress biomarkers in healthy men: a randomized clinical trial

JP Richie Jr, A Das, AM Calcagnotto, R Sinha… - Cancer Prevention …, 2014 - AACR
Epidemiologic and laboratory studies indicate that dietary selenium protects against prostate
cancer. Results from clinical trials suggest that selenium-enriched yeast (SY) but not …

[HTML][HTML] Selenium targets resistance biomarkers enhancing efficacy while reducing toxicity of anti-cancer drugs: Preclinical and clinical development

Y Zakharia, A Bhattacharya, YM Rustum - Oncotarget, 2018 - ncbi.nlm.nih.gov
Selenium (Se)-containing molecules exert antioxidant properties and modulate targets
associated with tumor growth, metastasis, angiogenesis, and drug resistance. Prevention …