Vascularization of 3D models represents a major challenge of tissue engineering and a key
prerequisite for their clinical and industrial application. The use of prevascularized models …

As engineered tissues progress toward therapeutically relevant length scales and cell
densities, it is critical to deliver oxygen and nutrients throughout the tissue volume via …

Liver regeneration is a well-orchestrated process that is typically studied in animal models.
Although previous animal studies have offered many insights into liver regeneration, human …

Neuroblastoma (NB) is the most common extracranial tumor in children resulting in
substantial morbidity and mortality. A deeper understanding of the NB tumor …

Bioartificial liver (BAL) system has become a promising alternative to traditional liver
transplantation in rescuing acute liver failure (ALF) patients. Herein, inspired by natural …

Engineered nanomaterials are bestowed with certain inherent physicochemical properties
unlike their parent materials, rendering them suitable for the multifaceted needs of state-of …

Abstract Heme oxygenase 1 (HO-1), also known as heat shock protein 32 (HSP32), is a
stress-inducible enzyme. In the past, it was believed to participate in maintaining cell …

Vascular atresia are often treated via transcatheter recanalization or surgical vascular
anastomosis due to congenital malformations or coronary occlusions. The cellular response …

Although there are various pre‐existing technologies for engineering vasculatures,
multiscale modeling of the architecture of human vasculature at a capillary scale remains a …

Scars are composed of stiff collagen fibers, which contract strongly owing to the action of
myofibroblasts. To explore the substances that modulate scar contracture, the fibroblast …