Temozolomide nano enabled medicine: promises made by the nanocarriers in glioblastoma therapy

PS Yasaswi, K Shetty, KS Yadav - Journal of Controlled Release, 2021 - Elsevier
Glioblastoma multiforme (GBM) is abnormal cell proliferation of glial cells. GBM is the grade
IV glioma brain cancer which is life-threatening to many individuals affected by this cancer …

[HTML][HTML] DNA tetrahedral nanostructures for the biomedical application and spatial orientation of biomolecules

W Wang, M Lin, W Wang, Z Shen, ZS Wu - Bioactive Materials, 2024 - Elsevier
DNA not only plays a vital role in nature as fundamental hereditary material for storing
genetic material, but also serves as well-defined functional material, for example, building …

Folic acid-functionalized, condensed magnetic nanoparticles for targeted delivery of doxorubicin to tumor cancer cells overexpressing the folate receptor

A Angelopoulou, A Kolokithas-Ntoukas, C Fytas… - ACS …, 2019 - ACS Publications
This study concerns the development of folic acid (FA)-functionalized iron oxide condensed
colloidal magnetic clusters for a more selective delivery of doxorubicin (DOX) to tumor …

Polymeric nanoparticles for drug delivery in glioblastoma: State of the art and future perspectives

F Madani, SS Esnaashari, TJ Webster… - Journal of Controlled …, 2022 - Elsevier
Glioblastoma (GBM) is an aggressive, fatal and malignant primary brain tumor. Despite the
current standard treatment for glioblastoma patients including neurosurgical resection …

Multimodal targeting of glioma with functionalized nanoparticles

HE Marei - Cancer Cell International, 2022 - Springer
The most common and aggressive primitive intracranial tumor of the central nervous system
is the glioma. The blood–brain barrier (BBB) has proven to be a significant obstacle to the …

Liposomal-based formulations: a path from basic research to temozolomide delivery inside glioblastoma tissue

RM Amarandi, A Ibanescu, E Carasevici, L Marin… - Pharmaceutics, 2022 - mdpi.com
Glioblastoma (GBM) is a lethal brain cancer with a very difficult therapeutic approach and
ultimately frustrating results. Currently, therapeutic success is mainly limited by the high …

Docetaxel-loaded folate-modified TPGS-transfersomes for glioblastoma multiforme treatment

MT Luiz, JSR Viegas, JP Abriata, LB Tofani… - Materials Science and …, 2021 - Elsevier
Glioblastoma multiforme (GBM) is a first primary Central Nervous System tumor with high
incidence and lethality. Its treatment is hampered by the difficulty to overcome the blood …

Thermosensitive magnetic nanoparticles exposed to alternating magnetic field and heat-mediated chemotherapy for an effective dual therapy in rat glioma model

R Afzalipour, S Khoei, S Khoee, S Shirvalilou… - … , Biology and Medicine, 2021 - Elsevier
The goal of this study was to develop a new method based on Oncothermia with
concomitant use of the temozolomide (TMZ)-loaded magnetic nanoparticles conjugated with …

Improving temozolomide biopharmaceutical properties in glioblastoma multiforme (GBM) treatment using GBM-targeting nanocarriers

LD Di Filippo, JH Azambuja, JAP Dutra, MT Luiz… - European Journal of …, 2021 - Elsevier
Glioblastoma multiforme (GBM) is the most common primary brain cancer. GBM has
aggressive development, and the pharmacological treatment remains a challenge due to …

Sensitization of glioblastoma cancer cells to radiotherapy and magnetic hyperthermia by targeted temozolomide-loaded magnetite tri-block copolymer nanoparticles …

SE Minaei, S Khoei, S Khoee, SR Mahdavi - Life Sciences, 2022 - Elsevier
Aims Recently, the development of new strategies in the treatment and diagnosis of cancer
cells such as thermo-radiation-sensitizer and theranostic agents have received a great deal …