This report provides a review of early and late effects of radiation in normal tissues and
organs with respect to radiation protection. It was instigated following a recommendation in …

Cytokines function in many roles that are highly relevant to radiation research. This review
focuses on how cytokines are structurally organized, how they are induced by radiation, and …

Purpose: The lung is the major dose-limiting organ for radiotherapy of cancer in the thoracic
region. The pathogenesis of radiation-induced lung injury at the molecular level is still …

Radiation therapy is one of the most common treatment strategies for thorax malignancies.
One of the considerable limitations of this therapy is its toxicity to normal tissue. The lung is …

There is a rapid onset of organizing alveolitis/fibrosis at 120–140 d after whole lung
irradiation of C57BL/6J mice. To test the hypothesis that circulating cells of bone marrow …

In humans, a number of genetic factors have been linked to the development of fibrosis in a
variety of different organs. Seeking a wider understanding of this observation in man is …

Fibrosis, characterized by the accumulation of collagen, is a consequence of a chronic
inflammatory response. The purpose of this study was to determine if tumor necrosis factor α …

Purpose: To investigate cytokine gene expression in the lung after single and fractionated
doses of radiation, and to investigate the effect of steroids and the genetic background …

The individual susceptibility to pulmonary fibrosis (PF) remains a mystery, suggesting a role
for genetic predisposition. The pathogenesis of PF involves a multitude of factors mediating …

Purpose: There is increasing concern that, since the Cold War era, there has been little
progress regarding the availability of medical countermeasures in the event of either a …