On modeling

DS Novikov, VG Kiselev… - Magnetic resonance in …, 2018 - Wiley Online Library
Mapping tissue microstructure with MRI holds great promise as a noninvasive window into
tissue organization at the cellular level. Having originated within the realm of diffusion NMR …

Quantifying brain microstructure with diffusion MRI: Theory and parameter estimation

DS Novikov, E Fieremans, SN Jespersen… - NMR in …, 2019 - Wiley Online Library
We review, systematize and discuss models of diffusion in neuronal tissue, by putting them
into an overarching physical context of coarse‐graining over an increasing diffusion length …

[HTML][HTML] Connectome 2.0: Developing the next-generation ultra-high gradient strength human MRI scanner for bridging studies of the micro-, meso-and macro …

SY Huang, T Witzel, B Keil, A Scholz, M Davids, P Dietz… - NeuroImage, 2021 - Elsevier
The first phase of the Human Connectome Project pioneered advances in MRI technology
for mapping the macroscopic structural connections of the living human brain through the …

Noninvasive quantification of axon radii using diffusion MRI

J Veraart, D Nunes, U Rudrapatna, E Fieremans… - elife, 2020 - elifesciences.org
Axon caliber plays a crucial role in determining conduction velocity and, consequently, in the
timing and synchronization of neural activation. Noninvasive measurement of axon radii …

[HTML][HTML] Challenges for biophysical modeling of microstructure

IO Jelescu, M Palombo, F Bagnato… - Journal of Neuroscience …, 2020 - Elsevier
The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25
years. In this review, we dwell on the various challenges along the journey of bringing a …

On the scaling behavior of water diffusion in human brain white matter

J Veraart, E Fieremans, DS Novikov - NeuroImage, 2019 - Elsevier
Abstract Development of therapies for neurological disorders depends on our ability to non-
invasively diagnose and monitor the progression of underlying pathologies at the cellular …

Highly efficient head‐only magnetic field insert gradient coil for achieving simultaneous high gradient amplitude and slew rate at 3.0 T (MAGNUS) for brain …

TKF Foo, ET Tan, ME Vermilyea, Y Hua… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose To develop a highly efficient magnetic field gradient coil for head imaging that
achieves 200 mT/m and 500 T/m/s on each axis using a standard 1 MVA gradient driver in …

MRI with ultrahigh field strength and high-performance gradients: challenges and opportunities for clinical neuroimaging at 7 T and beyond

B Vachha, SY Huang - European radiology experimental, 2021 - Springer
Research in ultrahigh magnetic field strength combined with ultrahigh and ultrafast gradient
technology has provided enormous gains in sensitivity, resolution, and contrast for …

[HTML][HTML] The sensitivity of diffusion MRI to microstructural properties and experimental factors

M Afzali, T Pieciak, S Newman, E Garyfallidis… - Journal of Neuroscience …, 2021 - Elsevier
Diffusion MRI is a non-invasive technique to study brain microstructure. Differences in the
microstructural properties of tissue, including size and anisotropy, can be represented in the …

Along-axon diameter variation and axonal orientation dispersion revealed with 3D electron microscopy: implications for quantifying brain white matter microstructure …

HH Lee, K Yaros, J Veraart, JL Pathan… - Brain Structure and …, 2019 - Springer
Tissue microstructure modeling of diffusion MRI signal is an active research area striving to
bridge the gap between macroscopic MRI resolution and cellular-level tissue architecture …