Cyclosporine A (CsA) is a widely used immunosuppressive agent that greatly reduces the
rates of kidney-, heart-, and liver-transplant rejection. However, CsA nephrotoxicity is a …

Hydroxytyrosol is one of the main phenolic components of olive oil. It is present in the fruit
and leaf of the olive (Olea europaea L.). During the past decades, it has been well …

In this study, we investigated the mechanisms by which puerarin alleviates osteoclast-
related loss of bone mass in ovariectomy (OVX)-induced osteoporosis model mice. Puerarin …

Caffeic acid (CAA) and chlorogenic acid (CHA) are important members of hydroxycinnamic
acid with natural antioxidant and cardio-protective properties. The present study aimed to …

As olive oil is the main source of calories in the Mediterranean diet, a large number of
studies have been carried out to characterize its role in various diseases and exploitation for …

The purpose of this study was to evaluate the protective effect of ethanolic olive fruit extract
(OFE) and its phenolic compound, oleuropein (OLE), against hepato-renal toxicity induced …

Ochratoxin-A (OTA) is a mycotoxin that is a common contaminant of food products for both
humans and animals. This mycotoxin has several toxic effects. In particular, ochratoxin has …

There are more than 100 different biophenols reported in olive samples. This chapter covers
the chemistry, pharmacodynamics, pharmacokinetics, posology, adverse effects, and …

Abstract Alzheimer's disease (AD), the most common type of dementia, is a devastating
neurodegenerative disease characterized by progressive neuro-cognitive dysfunction. In our …

Focal segmental glomerulosclerosis (FSGS) is a kidney disease with progressive glomerular
scarring and a clinical presentation of nephrotic syndrome. FSGS is a common primary …