Mechanisms of ethanol tolerance in Saccharomyces cerevisiae

M Ma, ZL Liu - Applied microbiology and biotechnology, 2010 - Springer
Saccharomyces cerevisiae is a superb ethanol producer, yet is also sensitive to higher
ethanol concentrations especially under high gravity or very high gravity fermentation …

Metabolic cycles as an underlying basis of biological oscillations

BP Tu, SL McKnight - Nature reviews Molecular cell biology, 2006 - nature.com
The evolutionary origins of periodic phenomena in biology, such as the circadian cycle, the
hibernation cycle and the sleep–wake cycle, remain a mystery. We discuss the concept of …

Autonomous metabolic oscillations robustly gate the early and late cell cycle

A Papagiannakis, B Niebel, EC Wit, M Heinemann - Molecular cell, 2017 - cell.com
Eukaryotic cell division is known to be controlled by the cyclin/cyclin dependent kinase
(CDK) machinery. However, eukaryotes have evolved prior to CDKs, and cells can divide in …

Cyclic changes in metabolic state during the life of a yeast cell

BP Tu, RE Mohler, JC Liu… - Proceedings of the …, 2007 - National Acad Sciences
Budding yeast undergo robust oscillations in oxygen consumption during continuous growth
in a nutrient-limited environment. Using liquid chromatography-mass spectrometry and …

The Cell Cycle–Regulated Genes of Schizosaccharomyces pombe

A Oliva, A Rosebrock, F Ferrezuelo, S Pyne… - PLoS …, 2005 - journals.plos.org
Many genes are regulated as an innate part of the eukaryotic cell cycle, and a complex
transcriptional network helps enable the cyclic behavior of dividing cells. This transcriptional …

The yeast cyclin-dependent kinase routes carbon fluxes to fuel cell cycle progression

JC Ewald, A Kuehne, N Zamboni, JM Skotheim - Molecular cell, 2016 - cell.com
Cell division entails a sequence of processes whose specific demands for biosynthetic
precursors and energy place dynamic requirements on metabolism. However, little is known …

Driving the cell cycle through metabolism

L Cai, BP Tu - Annual review of cell and developmental biology, 2012 - annualreviews.org
For unicellular organisms, the decision to enter the cell cycle can be viewed most
fundamentally as a metabolic problem. A cell must assess its nutritional and metabolic status …

Cyclin-dependent kinase co-ordinates carbohydrate metabolism and cell cycle in S. cerevisiae

G Zhao, Y Chen, L Carey, B Futcher - Molecular cell, 2016 - cell.com
Cyclin-dependent kinases (CDKs) control cell division in eukaryotes by phosphorylating
proteins involved in division. But successful proliferation requires co-ordination between …

Dynamic behavior of microbial populations in stirred bioreactors simulated with Euler− Lagrange methods: traveling along the lifelines of single cells

A Lapin, D Müller, M Reuss - Industrial & engineering chemistry …, 2004 - ACS Publications
In the present work, an Euler− Lagrange approach has been applied to characterize the
behavior of a heterogeneous cell population in a stirred-tank bioreactor with nonideal …

[图书][B] Bioreactors: design, operation and novel applications

CF Mandenius - 2016 - books.google.com
In this expert handbook both the topics and contributors are selected so as to provide an
authoritative view of possible applications for this new technology. The result is an up-to …