Enterococci have been recognized as important hospital-acquired pathogens in recent
years, and isolates of E. faecalis and E. faecium are the third-to fourth-most prevalent …

Extrachromosomal elements are ubiquitous in the prokaryotic world and play important roles
in the adaptation and survival of cell populations, especially in changing environments …

Firmicutes constitutes one of the dominant bacteria phyla of human and animal gut
microbiota. It comprises a number of genera of outstanding relevance in health care and …

Centromeres are critical structures involved in chromosome segregation, maintaining
genomic stability, and facilitating the accurate transmission of genetic information. They are …

Low copy number plasmids in bacteria require segregation for stable inheritance through
cell division. This is often achieved by a parABC locus, comprising an ATPase ParA, DNA …

The pheromone-responsive conjugative plasmids of Enterococcus faecalis and the
multiresistance plasmids pSK1 and pSK41 of Staphylococcus aureus are among the best …

DNA segregation or partition is an essential process that ensures stable genome
transmission. In prokaryotes, partition is best understood for plasmids, which serve as …

ABSTRACT A tetracycline-resistant (Tetr) dairy Enterococcus faecium isolate designated
M7M2 was found to carry both tet (M) and tet (L) genes on a 19.6-kb plasmid. After …

pSM19035 is a low-copy-number theta-replicating plasmid, which belongs to the Inc18
family. Plasmids of this family, which show a modular organization, are functional in …

Our previous study established the human multi-drug-resistant cholangiocarcinoma cell line
QBC939/ADM. In this study, we investigate further the ability of tamoxifen (TAM) to reverse …