Fundamentals of fractional laser-assisted drug delivery: an in-depth guide to experimental methodology and data interpretation

E Wenande, RR Anderson, M Haedersdal - Advanced drug delivery …, 2020 - Elsevier
In the decade since their advent, ablative fractional lasers have emerged as powerful tools
to enhance drug delivery to and through the skin. Effective and highly customizable, laser …

Recent insights into cutaneous immunization: How to vaccinate via the skin

L Engelke, G Winter, S Hook, J Engert - Vaccine, 2015 - Elsevier
Technologies and strategies for cutaneous vaccination have been evolving significantly
during the past decades. Today, there is evidence for increased efficacy of cutaneously …

In situ tumour arrays reveal early environmental control of cancer immunity

G Ortiz-Muñoz, M Brown, CB Carbone… - Nature, 2023 - nature.com
The immune phenotype of a tumour is a key predictor of its response to immunotherapy,,–.
Patients who respond to checkpoint blockade generally present with immune-inflamed …

Laser microporation facilitates topical drug delivery: a comprehensive review about preclinical development and clinical application

Y Zhao, J Voyer, Y Li, X Kang… - Expert opinion on drug …, 2023 - Taylor & Francis
Introduction Topical drug delivery is highly attractive and yet faces tissue barrier challenges.
Different physical and chemical methods have been explored to facilitate topical drug …

Current knowledge of immunomodulation strategies for chronic skin wound repair

P Heydari, M Kharaziha, J Varshosaz… - … Research Part B …, 2022 - Wiley Online Library
In orchestrating the wound healing process, the immune system plays a critical role. Hence,
controlling the immune system to repair skin defects is an attractive approach. The highly …

Effects of chemical and physical enhancement techniques on transdermal delivery of 3-fluoroamphetamine hydrochloride

A Puri, KS Murnane, BE Blough, AK Banga - International Journal of …, 2017 - Elsevier
The present study investigated the passive transdermal delivery of 3-fluoroamphetamine
hydrochloride (PAL-353) and evaluated the effects of chemical and physical enhancement …

Modulated delivery of donepezil using a combination of skin microporation and iontophoresis

M Kale, T Kipping, AK Banga - International journal of pharmaceutics, 2020 - Elsevier
The present study investigated the transdermal delivery of donepezil hydrochloride across
dermatomed porcine ear skin using passive and physical enhancement techniques. In vitro …

Transdermal delivery of peptide and protein drugs: Strategies, advantages and disadvantages

L Long, J Zhang, Z Yang, Y Guo, X Hu… - Journal of Drug Delivery …, 2020 - Elsevier
Peptide and protein drugs (PPDs) that possess the advantages of high specificity and
tolerance, and low immunogenicity can effectively treat diabetes, osteoporosis, cancer, and …

Lessons learned from the first decade of laser-assisted drug delivery

T Searle, FR Ali, F Al-Niaimi - Dermatology and therapy, 2021 - Springer
Laser-assisted drug delivery augments the distribution and penetration of topically applied
treatments, leading to enhanced delivery and bioavailability. We discuss the therapeutic …

Evidence-based clinical practice guidelines for laser-assisted drug delivery

JG Labadie, SA Ibrahim, B Worley, BY Kang… - JAMA …, 2022 - jamanetwork.com
Importance Laser-assisted drug delivery (LADD) is used for various medical and cosmetic
applications. However, there is insufficient evidence-based guidance to assist clinicians …