[HTML][HTML] Liposomes: Structure, composition, types, and clinical applications

H Nsairat, D Khater, U Sayed, F Odeh, A Al Bawab… - Heliyon, 2022 - cell.com
Liposomes are now considered the most commonly used nanocarriers for various potentially
active hydrophobic and hydrophilic molecules due to their high biocompatibility …

[HTML][HTML] Polymersome-based protein drug delivery–quo vadis?

MG Gouveia, JP Wesseler, J Ramaekers… - Chemical Society …, 2023 - pubs.rsc.org
Protein-based therapeutics are an attractive alternative to established therapeutic
approaches and represent one of the fastest growing families of drugs. While many of these …

Biopolymer-liposome hybrid systems for controlled delivery of bioactive compounds: Recent advances

C Tan, J Wang, B Sun - Biotechnology Advances, 2021 - Elsevier
Conventional liposomes still face many challenges associated with the poor physical and
chemical stability, considerable loss of encapsulated cargo, lack of stimulus responsiveness …

[HTML][HTML] Recent advances in using liposomes for delivery of nucleic acid-based therapeutics

H Nsairat, W Alshaer, F Odeh, E Esawi, D Khater… - OpenNano, 2023 - Elsevier
Nucleic acid therapeutics are rapidly expanding because of recent advancements in
production and purification. This class of therapeutics may change the field of disease …

[HTML][HTML] Nanoformulations to enhance the bioavailability and physiological functions of polyphenols

B Yang, Y Dong, F Wang, Y Zhang - Molecules, 2020 - mdpi.com
Polyphenols are micronutrients that are widely present in human daily diets. Numerous
studies have demonstrated their potential as antioxidants and anti-inflammatory agents, and …

[HTML][HTML] Quality by design approach in liposomal formulations: Robust product development

W Alshaer, H Nsairat, Z Lafi, OM Hourani, A Al-Kadash… - Molecules, 2022 - mdpi.com
Nanomedicine is an emerging field with continuous growth and differentiation. Liposomal
formulations are a major platform in nanomedicine, with more than fifteen FDA-approved …

[HTML][HTML] Lipid nanostructures for targeting brain cancer

H Nsairat, D Khater, F Odeh, F Al-Adaileh, S Al-Taher… - Heliyon, 2021 - cell.com
Advancements in both material science and bionanotechnology are transforming the health
care sector. To this end, nanoparticles are increasingly used to improve diagnosis …

[HTML][HTML] Lipid-hybrid cell-derived biomimetic functional materials: A state-of-the-art multifunctional weapon against tumors

WS Liu, LL Wu, CM Chen, H Zheng, J Gao, ZM Lu… - Materials Today Bio, 2023 - Elsevier
Tumors are among the leading causes of death worldwide. Cell-derived biomimetic
functional materials have shown great promise in the treatment of tumors. These materials …

[HTML][HTML] Grafting of anti-nucleolin aptamer into preformed and remotely loaded liposomes through aptamer-cholesterol post-insertion

H Nsairat, IS Mahmoud, F Odeh, D Abuarqoub… - RSC …, 2020 - pubs.rsc.org
A new combination strategy of an active loading and active targeting approach was applied
in this work. The liposomes actively loaded with Curcumin (CRM)(LipCRM) were decorated …

Curcumin-loaded liposomes prepared from bovine milk and krill phospholipids: Effects of chemical composition on storage stability, in-vitro digestibility and anti …

Y Wu, B Mou, S Song, CP Tan, OM Lai, C Shen… - Food Research …, 2020 - Elsevier
Present study prepared curcumin liposomes with high encapsulation efficiency (> 70%)
using bovine milk and krill phospholipids; and investigated the effects of phospholipids …