Ample evidence suggests that sleep and pain are related. However, many questions remain
about the direction of causality in their association, as well as mechanisms that may account …

During the last 30 years, there has been a substantial increase in the study of posttraumatic
stress disorder (PTSD). Several high-profile traumatic events, such as the wars in …

Context. Intense acute pain afflicts millions of patients each year. Despite the recently
increased focus on the importance of pain control, management of acute pain has remained …

Epidemiological, cross-sectional, and prospective studies suggest that insomnia, chronic
pain, and depression frequently co-occur and are mutually interacting conditions. However …

Chronic pain has been associated with sleep disturbances in a bidirectional manner, with
pain disrupting sleep, and sleep deprivation or disturbance increasing pain. This …

Sleep has a homeostatic role in the regulation of the immune system and serves to constrain
activation of inflammatory signalling and expression of cellular inflammation. In patients with …

This systematic review and meta-analysis aimed at evaluating the role of sleep disturbances
and sleep disorders in influencing presence and intensity of chronic postsurgical pain …

Objective Osteoarthritis (OA), a chronic degenerative joint disorder, is characterized by joint
pain. Emerging research demonstrates that a significant number of patients evidence central …

Abstract Study Objectives: We characterized sleep disorder rates in temporomandibular joint
disorder (TMD) and evaluated possible associations between sleep disorders and …

Cross-sectional research in clinical samples, as well as experimental studies in healthy
adults, suggests that the experiences of pain and sleep are bi-directionally connected …